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Article
Preparation of monodisperse, superparamagnetic, luminescent, and multifunctional PGMA microspheres with amino-groups
Micron-sized, monodisperse, superparamagnetic, luminescent composite poly(glycidyl methacrylate) (PGMA) microspheres with functional amino-groups were successfully synthesized in this study. The process of pre...
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Article
Repair effect of diabetic ulcers with recombinant human epidermal growth factor loaded by sustained-release microspheres
In this study the w/o/w extraction-evaporation technique was adopted to prepare poly(lactic-co-glycolic acid) (PLGA) microspheres loading recombinant human epidermal growth factor (rhEGF). The microspheres were c...
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Chapter
A WSN Range Method Based on the Frequency Difference Measurement
A novel WSN location algorithm based on the frequency difference is proposed. The algorithm arbitrarily chooses two anchor nodes to send the frequency modulation signals, the distances between the unknown node...
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Article
Methods for assessing regional glacial lake variation and hazard in the southeastern Tibetan Plateau: a case study from the Boshula mountain range, China
Glaciers on the Tibetan Plateau are undergoing an accelerating retreat under climatic warming, with the immediate result of glacial lake outburst floods (GLOFs) becoming increasingly frequent. Glacial lakes in...
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Article
Short-term variability in the dates of the Indian monsoon onset and retreat on the southern and northern slopes of the central Himalayas as determined by precipitation stable isotopes
This project launched the first study to compare the stable isotopes (δ18O and δD) in daily precipitation at Kathmandu (located on the southern slope of the central Himalayas) and Tingri (located on the northern...
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Article
Retreat rates of debris-covered and debris-free glaciers in the Koshi River Basin, central Himalayas, from 1975 to 2010
Debris-covered glaciers are common in the Himalayas and play a key role in understanding future regional water availability and management. Previous studies of regional glacial changes have often neglected deb...
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Article
Open AccessPLGA-based control release of Noggin blocks the premature fusion of cranial sutures caused by retinoic acid
Craniosynostosis (CS), the premature and pathological fusion of cranial sutures, is a relatively common developmental disorder. Elucidation of the pathways involved and thus therapeutically targeting it would ...
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Chapter and Conference Paper
The Measurement Model of the Matching Degree Between Service Innovation Strategy and Innovation Capability of Manufacturing Enterprises and Its Application
By analyzing the matching relationship between manufacturing enterprise service innovation strategy and innovation capability, this paper constructs the evaluation index system and measurement method of manufa...
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Article
Open AccessTooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
Tooth defect and tooth loss are common clinical diseases in stomatology. Compared with the traditional oral restoration treatment, tooth regeneration has unique advantages and is currently the focus of oral bi...
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Article
Open AccessControl of mesenchymal stem cell biology by histone modifications
Mesenchymal stem cells (MSCs) are considered the most promising seed cells for regenerative medicine because of their considerable therapeutic properties and accessibility. Fine-tuning of cell biological proce...
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Article
Open AccessTemporal induction of Lhx8 by optogenetic control system for efficient bone regeneration
The spatiotemporal regulation of essential genes is crucial for controlling the growth and differentiation of cells in a precise manner during regeneration. Recently, optogenetics was considered as a potent te...
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Article
Understanding the 2004 glacier detachment in the Amney Machen Mountains, northeastern Tibetan Plateau, via multi-phase modeling
Glacial detachment is a newly emerged glacial hazard type, and more than 20 cases have been identified worldwide. The **ao Ma Glacier in the Amney Machen Mountains, northeastern Tibetan Plateau, experienced an...
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Article
Open AccessGenetically engineered CXCR4-modified exosomes for delivery of miR-126 mimics to macrophages alleviate periodontitis
Biofilm-related diseases are a group of diseases that tolerate antimicrobial chemotherapies and therefore are refractory to treatment. Periodontitis, a non-device chronic biofilm disease induced by dental plaq...
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Article
Underestimated mass loss from lake-terminating glaciers in the greater Himalaya
Long-term satellite-based observations have helped quantify glacier mass change and the response of the hydrosphere to glacier changes. However, subaqueous mass loss associated with lake-terminating glaciers i...
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Article
Total mesialization of the mandibular dentition using a mini-implant-supported device
Total mandibular arch mesialization using mini-implants is challenging due to anatomic limitations. The aim of this study was to introduce a mini-implant-supported device for total mesialization of the mandibu...
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Article
Open AccessEnhanced glacial lake activity threatens numerous communities and infrastructure in the Third Pole
Glacial lake outburst floods (GLOFs) are among the most severe cryospheric hazards in the Third Pole, encompassing the Tibetan Plateau and surrounding Himalayas, Hindu Kush, and Tianshan Mountains. Recent stud...
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Article
Glacier retreat and lake outburst floods in the central Himalayan region from 2000 to 2022
Recent research on the Himalayan cryosphere has increasingly been focused on climate uncertainty and regional variations, considering features such as glacier recession, lake expansion, outburst floods, and re...
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Article
Open AccessHeterogeneous changes in global glacial lakes under coupled climate warming and glacier thinning
Global glacial lakes have expanded markedly in recent decades, accompanied by many catastrophic glacial lake outburst floods. However, our understanding of glacial lake evolution and connections with global wa...
