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Article
Open AccessRegio- and enantioselective CuH-catalyzed 1,2- and 1,4-hydrosilylation of 1,3-enynes
We report a copper-catalyzed ligand-controlled selective 1,2- and 1,4-hydrosilylation of 1,3-enynes, which furnishes enantiomerically enriched propargyl- and 1,2-allenylsilane products in high yields with exce...
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Article
A systematic review: on the mercaptoacid metabolites of acrylamide, N-acetyl-S-(2-carbamoylethyl)-L-cysteine
Acrylamide is widely found in a variety of fried foods and cigarettes and is not only neurotoxic and carcinogenic, but also has many potential toxic effects. The current assessment of acrylamide intake through...
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Article
Characterization of iron, sulfur, and phosphorus diagenesis in muddy sediments of the South Yellow Sea using the diffusive gradients in thin films (DGT) technique
The muddy sediments of the central South Yellow Sea (SYS) are not only an important depocenter, but also an important area for early diagenesis. A systematic study of the interlinked sulfur (S), iron (Fe), and...
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Article
Sulfur, iron, and phosphorus geochemistry in an intertidal mudflat impacted by shellfish aquaculture
Dissolved sulfide, iron (Fe), and phosphorus (P) in a mudflat (Jiaozhou Bay, China) impacted by shellfish aquaculture were measured in situ by the diffusive gradients in thin films (DGT) technique. A combinati...
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Article
Effect of Copper on the Microstructure and Properties of Phosphorus Cast Iron for the Anode of Aluminum Electrolyzer
The effect of copper content on the microstructure and properties of Phosphorus Cast Iron for the anode of aluminum electrolyzer is studied in this paper. After adding 0.41–1.52 wt.% Cu in Phosphorus Cast Iron...
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Article
Using information flow analysis to detect implicit information leaks for web service composition
Information leak, which can undermine the compliance of web-service-composition business processes for some policies, is one of the major concerns in web service composition. We present an automated and effect...
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Article
Ethaselen: a novel organoselenium anticancer agent targeting thioredoxin reductase 1 reverses cisplatin resistance in drug-resistant K562 cells by inducing apoptosis
It has been reported that Ethaselen shows inhibitory effects on thioredoxin reductase (TrxR) activity and human tumor cell growth. In order to find an efficient way to reverse cisplatin resistance, we investig...
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Article
Genistein Inhibits Aβ25–35-Induced Synaptic Toxicity and Regulates CaMKII/CREB Pathway in SH-SY5Y Cells
Genistein (Gen), as a functional food in human diet, has shown many beneficial effects on neurodegenerative diseases such as Alzheimer’s disease (AD). But the neuroprotective mechanism of Gen is not clear. Be...
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Article
The Oxysterol 27-Hydroxycholesterol Increases Oxidative Stress and Regulate Nrf2 Signaling Pathway in Astrocyte Cells
The disturbance in cholesterol metabolism has been considered as a cause of alzheimer’s disease (AD), which dues to the oxidative damage and cell apoptosis in the brain. We aimed to investigate the toxicity an...
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Article
Soy Isoflavone Antagonizes the Oxidative Cerebrovascular Injury Induced by β-Amyloid Peptides 1–42 in Rats
Numerous evidences have shown that the antioxidative properties of soy isoflavone (SIF) have beneficial effects on prophylaxis of neurodegeneration, however, the mechanism is still not fully illustrated. As ce...
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Article
Beta Amyloid Peptide (25-35) Leading to Inflammation Through Toll-Like Receptors and the Anti-inflammatory Effect of Genistein in BV-2 Cells
Genistein, the main soy isoflavone component, has received much attention for its potential multifunction. Here, we reported that in BV-2 cells, genistein significantly inhibited beta amyloid peptides 25-35 (A...
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Article
Genistein alleviates the mitochondria-targeted DNA damage induced by β-amyloid peptides 25–35 in C6 glioma cells
Reactive oxygen species (ROS) are mainly produced by mitochondria which can cause oxidative stress. It has been considered that mitochondrial damage induced by oxidative stress is related to Alzheimer’s diseas...
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Article
Genistein inhibits mitochondrial-targeted oxidative damage induced by beta-amyloid peptide 25–35 in PC12 cells
The antioxidative properties of genistein (Gen) have been demonstrated by our previous studies and others, but its potential mechanism was not very clear. Because of the key role of mitochondria in oxidant pro...
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Article
Discrepancy between radiographic shoulder balance and cosmetic shoulder balance in adolescent idiopathic scoliosis patients with double thoracic curve
Shoulder balance is one of the key components to the body deformity in adolescent idiopathic scoliosis (AIS) patients with double thoracic curve and shoulder cosmesis plays an important role in patients’ satis...
