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    Article

    Orthogonal Constant-Amplitude Sequence Families for System Parameter Identification in Spectrally Compact OFDM

    In rectangularly-pulsed orthogonal frequency division multiplexing (OFDM) systems, constant-amplitude (CA) sequences are desirable to construct preamble/pilot waveforms to facilitate system parameter identific...

    Shih-Hao Lu, Char-Dir Chung, Wei-Chang Chen in Wireless Personal Communications (2024)

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    Chapter and Conference Paper

    Iterative Decision-Feedback Hybrid Equalization for CP-OTFS on Time-Varying Multipath Channels

    Cyclic-prefix orthogonal time frequency space (CP-OTFS) systems have gained great attention recently due to achievable prominent error performance characteristics in high-mobility wireless communication scenar...

    Shuen-Yu Tsai, Po-Jen Chen, Wei-Chang Chen in Recent Advances in Communication Networks … (2024)

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    Article

    β2-AR regulates the expression of AKR1B1 in human pancreatic cancer cells and promotes their proliferation via the ERK1/2 pathway

    Psychological stress has been recognized as a well-documented risk factor associated with β2-adrenergic receptor (β2-AR) in the development of pancreatic cancer. Aldo–keto reductase 1 member B1 (AKR1B1) is a p...

    Ming-Bing **ao, Dan-Dan **, Yu-Jie Jiao, Wen-Kai Ni in Molecular Biology Reports (2018)

  4. Article

    Open Access

    Novel circulating microRNAs expression profile in colon cancer: a pilot study

    To identify the expression profile of novel microRNAs (miRNAs) in colon cancer and evaluate their clinical applicability.

    Ya-nan Wang, Zhao-hua Chen, Wei-chang Chen in European Journal of Medical Research (2017)

  5. No Access

    Article

    A polymorphism in the promoter region of PD-L1 serves as a binding-site for SP1 and is associated with PD-L1 overexpression and increased occurrence of gastric cancer

    PD-L1 is a member of the B7 family co-inhibitory molecules and plays a critical role in tumor immune escape. In this study, we found a polymorphism rs10815225 in the PD-L1 promoter region was significantly associ...

    Li-Hua Tao, **n-Ru Zhou, Fu-Chao Li, Qi Chen in Cancer Immunology, Immunotherapy (2017)

  6. Article

    Open Access

    Evaluation and clinical significance of the stomach age model for evaluating aging of the stomach-a multicenter study in China

    A higher prevalence of chronic atrophic gastritis (CAG) occurs in younger adults in Asia. We used Stomach Age to examine the different mechanisms of CAG between younger adults and elderly individuals, and esta...

    Qin-Yan Gao, Zhen-Hua Wang, Yun Cui, Jian-Qiu Sheng, Kun-He Zhang in BMC Clinical Pathology (2014)

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    Article

    B7-H6 Protein Expression has no Prognostic Significance in Human Gastric Carcinoma

    B7-H6, a novel member of the B7 family which binds to NKp30 to trigger antitumor NK cell cytotoxicity and cytokine secretion. Recently, B7-H family has been reported to be a negative regulator of the immune re...

    **ao-Juan Chen, ** Shen, Guang-Bo Zhang, Wei-Chang Chen in Pathology & Oncology Research (2014)

  8. No Access

    Article

    Evaluation of Early Precut with Needle-Knife in Difficult Biliary Cannulation During ERCP

    There is scarce information on whether performing the precut procedure early rather than after several cannulation attempts is associated with different success and complication rates.

    Jian-hong Zhu, Qiang Liu, De-qing Zhang, Huang Feng in Digestive Diseases and Sciences (2013)

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    Article

    Screening and test of CD40 related signal transduction pathway in AGS cells and construction of gene silencing vector

    This study is designed to screen the CD40 related signal transduction pathway in AGS cells and construction of gene silencing vector. Analysis results showed 414 differential genes expression, including upregu...

    Rui Li, Wei-Chang Chen, Xue-Qin Pang, Wen-Yan Tian in Molecular Biology Reports (2013)

  10. No Access

    Article

    Effect of PI3K gene silencing on growth, migration and related proteins expression of CD40 signal-mediated gastric cancer cells

    In this study, we investigate effect of PI3K gene silencing on growth, migration and related proteins expression of CD40 signal-mediated gastric cancer cells. We observed that combination of sCD40L with PI3K s...

    Rui Li, Wei-Chang Chen, Xue-Qin Pang, Wen-Yan Tian in Molecular Biology Reports (2013)

  11. Article

    Open Access

    Increase of cyclooxygenase-2 inhibition with celecoxib combined with 5-FU enhances tumor cell apoptosis and antitumor efficacy in a subcutaneous implantation tumor model of human colon cancer

    The purpose of this study was to investigate the anti-tumor effect and explore the mechanisms of celecoxib (a selective cyclooxygenase-2 inhibitor) combined with 5-fluorouracil (5-FU) on the treatment of human...

    De-Qing Zhang, Qiang Guo, Jian-Hong Zhu in World Journal of Surgical Oncology (2013)

  12. No Access

    Article

    Combined effect of sCD40L and PI3K siRNA on transplanted tumours growth and microenvironment in nude mice with gastric cancer

    The objective of the paper is to investigate the combined effect of sCD40L and phosphatidylinositol 3-kinase (PI3K) siRNA on transplanted tumours growth and microenvironment in nude mice with gastric cancer. 4...

    Rui Li, Wei-Chang Chen, Xue-Qin Pang, Wen-Yan Tian in Molecular Biology Reports (2012)

  13. No Access

    Article

    CD40 signal expression in gastric cancer tissue and its correlation with prognosis of gastric cancer patients

    CD40 signaling plays a critical role in the survival rate of gastric cancer patients. Tumour samples were collected from 73 patients with who were diagnosed as gastric cancer in general surgery department in t...

    Rui Li, Wei-Chang Chen, Xue-Qin Pang, Wen-Yan Tian in Molecular Biology Reports (2012)

  14. No Access

    Article

    Gastric cancer cell lines AGS before and after CD40 signal activating

    The aim of this study was to investigate the molecular mechanisms underlying the antitumour effects of CD40L through analysing the change of genes expression profile in AGS using Affymetrix Gene Chip. Human ga...

    Rui Li, Xue-Qin Pang, Wei-Chang Chen, Ling Li, Wen-Yan Tian in Molecular Biology Reports (2012)

  15. No Access

    Article

    Influence of sCD40L on gastric cancer cell lines

    The CD40 signaling pathway plays a key role in tumor cell proliferation, differentiation, and apoptosis. Gastric cancer usually possesses a higher level of CD40 expression than normal tissue. We evaluated inhi...

    Rui Li, Wei-Chang Chen, Xue-Qin Pang, Wen-Yan Tian in Molecular Biology Reports (2011)

  16. No Access

    Article

    Extraction of essential oils from garlic (Allium sativum) using ligarine as solvent and its immunity activity in gastric cancer rat

    The solvent extraction (SE) of garlic essential oil (Allium sativum) was studied. A multivariate study based on a four-factor, three-level Box–Behnken design (BBD) was used to evaluate the influence of four major...

    Rui Li, Wei-chang Chen, Wei-peng Wang, Wen-yan Tian in Medicinal Chemistry Research (2010)

  17. No Access

    Article

    Analysis of the essential oil of magnolia and its effect on antioxidant enzyme activity, sCD40L and phosphorylate-activate Akt protein levels in gastric cancer mice

    The chemical composition of essential oil from magnolia collected in Suzhou city, China, was studied using gas chromatography-mass spectroscopy. Fifty-four volatile compounds were identified in the essential o...

    Rui Li, Wei-chang Chen, Wei-peng Wang, Wen-yan Tian in Medicinal Chemistry Research (2010)

  18. No Access

    Article

    Physical Simulation and Experimental Examination of ε-Cu Particles Dissolution Evolution During Welding of Copper Precipitation Strengthening Steel

    The kinetics of ε-CU particles dissolution in the matrix during welding of a copperprecipitation strengthening steel was determined by a combination of Gleeble™ physical simulation, TEM examination and hardnes...

    Qing-feng Wang, Cheng-jia Shang, Da-wei Chen in Journal of Iron and Steel Research Interna… (2007)