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Article
Establishment and validation of a nomogram model for predicting adverse pregnancy outcomes of pregnant women with adenomyosis
To establish a reliable nomogram model to predict the risk of major adverse pregnancy outcomes in pregnant women with adenomyosis, and to provide a reference tool for the hierarchical management and the prenat...
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Article
Exploring Imaging Genetic Markers of Alzheimer’s Disease Based on a Novel Nonlinear Correlation Analysis Algorithm
Alzheimer’s disease (AD) is an irreversible neurological disorder characterized by insidious onset. Identifying potential markers in its emergence and progression is crucial for early diagnosis and treatment. ...
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Article
Alkaline ceramidase 1–mediated platelet ceramide catabolism mitigates vascular inflammation and abdominal aortic aneurysm formation
Abdominal aortic aneurysm (AAA) is a highly lethal vascular disease. The role of platelets in AAA remains incompletely understood. Here we show that platelet ceramides, rather than other phospholipids, were el...
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Article
Open AccessGRSF1 antagonizes age-associated hypercoagulability via modulation of fibrinogen mRNA stability
Age-associated hypercoagulability is accompanied by the increase of plasma levels of some coagulation factors including fibrinogen which may contribute to the increased risk of cardiovascular, cerebrovascular,...
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Article
Open AccessAcoustic emission-based intelligent identification of piston aero-engine ignition advance angle anomalies
Ignition advance angle is one of the important factors affecting the performance of the engine, when it occurs abnormally will make the engine power and economy worse, and even cause serious damage to the engi...
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Article
Predicting the prognosis of hepatocellular carcinoma based on the interaction between pyroptosis, apoptosis, and necroptosis
Multiple programmed cell death pathways (pyroptosis, apoptosis, and necroptosis) are closely related to the progression of hepatocellular carcinoma (HCC). Furthermore, molecular interactions among pyroptotic, ...
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Article
Open AccessKnowledge fields and emerging trends about extracellular matrix in carotid artery disease from 1990 to 2021: analysis of the scientific literature
Stroke is a heavy burden in modern society, and carotid artery disease is a major cause. The role of the extracellular matrix (ECM) in the development and progression of carotid artery disease has become a pop...
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Article
Open AccessAblation of the gut microbiota alleviates high-methionine diet-induced hyperhomocysteinemia and glucose intolerance in mice
A high-methionine (HM) diet leads to hyperhomocysteinemia (HHcy), while gastrointestinal tissue is an important site of net homocysteine (Hcy) production. However, the role of the gut microbiota in host HHcy r...
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Article
A novel sinusoidal wavy interconnector for improved performance of SOFC
For the anode-supported solid oxide fuel cells (SOFC), the relatively thin cathode limits the oxygen transfer in-plane. In order to enhance the oxygen transfer in-plane, the interconnector with sinusoidal wavy...
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Article
High-throughput manufacturing of epitaxial membranes from a single wafer by 2D materials-based layer transfer process
Layer transfer techniques have been extensively explored for semiconductor device fabrication as a path to reduce costs and to form heterogeneously integrated devices. These techniques entail isolating epitaxi...
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Article
Open AccessCorrection: C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1+ M-MDSCs in relieving lupus-like symptoms
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Article
Open AccessCathepsin B in programmed cell death machinery: mechanisms of execution and regulatory pathways
Cathepsin B (CatB), a cysteine protease, is primarily localized within subcellular endosomal and lysosomal compartments. It is involved in the turnover of intracellular and extracellular proteins. Interest is ...
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Article
Open AccessB cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis
Hyperhomocysteinemia (HHcy) is a risk factor for chronic kidney diseases (CKDs) that affects about 85% CKD patients. HHcy stimulates B cells to secrete pathological antibodies, although it is unknown whether t...
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Article
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice
Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening cardiovascular disease with severe extracellular matrix (ECM) remodeling that lacks efficient early stage diagnosis and nonsurgical therapy....
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Article
Platinum nickel alloy-MXene catalyst with inverse opal structure for enhanced hydrogen evolution in both acidic and alkaline solutions
The development of an efficient Pt-based electrocatalyst in acidic and alkaline electrolytes is of great significance to the field of electrocatalytic hydrogen evolution. Herein, we report a strategy for in situ ...
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Chapter
Blockchain Scalability Fundamentals
Blockchains have been deeply diving into multiple applications, such as blockchain-assisted Internet of Things (IoT), business applications, security-enabled solutions, and many other applications in diverse f...
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Article
Open AccessIGFBP2 function as a novel biomarker for active lupus nephritis
In search for new targets for the diagnosis and treatment of lupus nephritis (LN), we employed TMT-liquid chromatography-triple quadrupole mass spectrometry (TMT-LC–MS/MS) combined with RNA-seq and identified ...
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Article
Open AccessHyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer’s disease
Progressive neuronal death is the key pathological feature of Alzheimer’s disease (AD). However, the molecular mechanisms underlying the neuronal death in AD patients have not been fully elucidated. Necroptosi...
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Article
Identify Biomarkers of Alzheimer's Disease Based on Multi-task Canonical Correlation Analysis and Regression Model
Imaging genetics using imaging technology is regarded as a neuroanatomical phenotype to evaluate gene single nucleotide polymorphisms and their effects on the structure and function of different brain regions....
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Article
Prediction of diagnosis results of rheumatoid arthritis patients based on autoantibodies and cost-sensitive neural network
To analyze and evaluate the effectiveness of the detection of single autoantibody and combined autoantibodies in patients with rheumatoid arthritis (RA) and related autoimmune diseases and establish a machine ...
