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Article
Genetic architecture of subcortical brain structures in 38,851 individuals
Subcortical brain structures are integral to motion, consciousness, emotions and learning. We identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate n...
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Article
Genomic segmental polymorphisms in inbred mouse strains
By analyzing genomic copy-number differences using high-resolution mouse whole-genome BAC arrays, we uncover substantial differences in regional DNA content between inbred strains of mice. The identification o...
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Article
An SSLP marker–anchored BAC framework map of the mouse genome
We have constructed a BAC framework map of the mouse genome consisting of 2,808 PCR-confirmed BAC clusters, using a previously described method1. Fingerprints of BACs from selected clusters confirm the accuracy o...
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Article
Engineering a mouse balancer chromosome
Balancer chromosomes are genetic reagents that are used in Drosophila melanogaster for stock maintenance and mutagenesis screens1. Despite their utility, balancer chromosomes are rarely used in mice because they ...