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    Activation of extrasynaptic GABAA receptors inhibits cyclothiazide-induced epileptiform activity in hippocampal CA1 neurons

    Extrasynaptic GABAA receptors (GABAARs)-mediated tonic inhibition is reported to involve in the pathogenesis of epilepsy. In this study, we used cyclothiazide (CTZ)-induced in vitro brain slice seizure model to e...

    Li Wan, Xu Liu, Zheng Wu, Wanting Ren, Shuzhen Kong… in Neuroscience Bulletin (2014)