-
Article
Open AccessElastic Stable Intramedullary Nailing Versus Plate Internal Fixation for Pediatric Diaphyseal Femur Fractures: A Systematic Review and Meta-analysis
Elastic stable intramedullary nailing (ESIN) and plates are currently the main internal fixation for treating Pediatric Diaphyseal Femur Fractures (PDFF), and the optimal choice of internal fixation is controv...
-
Article
The Role of H3K27me3-Mediated Th17 Differentiation in Ankylosing Spondylitis
Ankylosing spondylitis (AS) is a common chronic progressive inflammatory autoimmune disease. T helper 17 (Th17) cells are the major effector cells mediating AS inflammation. Histone 3 Lys 27 trimethylation (H3...
-
Article
Bi-objective Optimization for Resource-constrained Robust Construction Project Scheduling
Construction projects are often executed in complex environments, and various uncertain factors (e.g., bad weather, machine breakdown) prolong activity duration in practice, which may cause project completion ...
-
Article
Open AccessSARS-CoV-2-infected hiPSC-derived cardiomyocytes reveal dynamic changes in the COVID-19 hearts
The ongoing coronavirus disease 2019 (COVID-19) pandemic has had an enormous impact on our societies. Moreover, the disease’s extensive and sustained symptoms are now becoming a nonnegligible medical challenge...
-
Article
Open AccessDelineating the early dissemination mechanisms of acral melanoma by integrating single-cell and spatial transcriptomic analyses
Acral melanoma (AM) is a rare subtype of melanoma characterized by a high incidence of lymph node (LN) metastasis, a critical factor in tumor dissemination and therapeutic decision-making. Here, we employ sing...
-
Article
Open AccessMiR-217 regulates autophagy through OPG/RANKL/RANK in giant cell tumors
Increasing evidence suggests that microRNAs (miRNAs) play a crucial role in cancer development and progression. Our previous study showed remarkably lower levels of miR-217 in GCT cells and tissues, and miR-21...
-
Article
Open AccessDetermining the changes in metabolites of Dendrobium officinale juice fermented with starter cultures containing Saccharomycopsis fibuligera FBKL2.8DCJS1 and Lactobacillus paracasei FBKL1.3028 through untargeted metabolomics
The present study aimed to investigate the changes in volatile components and metabolites of Dendrobium officinale (D. officinale) juice fermented with starter cultures containing Saccharomycopsis fibuligera and
-
Article
A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy
Microphthalmia transcription factor (MITF) regulates melanocyte development and is the “lineage-specific survival” oncogene of melanoma. MITF is essential for melanoma initiation, progression, and relapse and has...
-
Article
An easy method for assessing frost susceptibility of soils: the freezing ring test
Frost heave induces deformation and damage to various facilities in cold regions and on artificially frozen ground. A convenient and quick way to assess frost susceptibility is favorable to deal with frost hea...
-
Chapter and Conference Paper
Research on Adaptive SSA for GNSS Landslide Multipath Effect Elimination
With Global Navigation Satellite System (GNSS), landslide monitoring often uses the short baseline relative positioning mode and its monitoring sequence is mainly affected by measurement noise and multipath ef...
-
Article
Reactive Procedure for Robust Project Scheduling under the Activity Disruptions
The baseline schedule may become infeasible when disruptions happen during the execution of project. This will lead to project delays and financial losses. In this paper, we developed a robust reactive optimiz...
-
Article
Open AccessA 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer
tRNA-derived small noncoding RNAs (sncRNAs) are mainly categorized into tRNA halves (tiRNAs) and fragments (tRFs). Biological functions of tiRNAs in human solid tumor are attracting more and more attention, bu...
-
Article
Open AccessA meta-analysis comparing tenotomy or tenodesis for lesions of the long head of the biceps tendon with concomitant reparable rotator cuff tears
The best treatment for lesions of the long head of the biceps tendon (LHBT) with concomitant reparable rotator cuff tears is still controversial. The purpose of the meta-analysis was to compare clinical outcom...
-
Article
Primary Squamous Cell Carcinoma in the Thyroid Gland: A Population-Based Analysis Using the SEER Database
To evaluate prognostic factors and treatment outcomes of primary squamous cell carcinoma in thyroid (PSCCTh) over the past decades using a large national database.
-
Article
Open AccessA region-resolved mucosa proteome of the human stomach
The human gastric mucosa is the most active layer of the stomach wall, involved in food digestion, metabolic processes and gastric carcinogenesis. Anatomically, the human stomach is divided into seven regions,...
-
Article
Open AccessAuthor Correction: A proteomic landscape of diffuse-type gastric cancer
The original version of this Article contained an error in the email address of the corresponding author Jun Qin. The correct email is jqin1965@126.com. The error has been corrected in the HTML and PDF version...
-
Article
Open AccessA proteomics landscape of circadian clock in mouse liver
As a circadian organ, liver executes diverse functions in different phase of the circadian clock. This process is believed to be driven by a transcription program. Here, we present a transcription factor (TF) ...
-
Article
Open AccessComparison of lateral entry with crossed entry pinning for pediatric supracondylar humeral fractures: a meta-analysis
The standard treatment for severe displaced pediatric supracondylar humeral fracture (SCHF) is closed reduction and percutaneous pin fixation. However, controversy persists concerning the optimal pin fixation ...
-
Article
Open AccessA proteomic landscape of diffuse-type gastric cancer
The diffuse-type gastric cancer (DGC) is a subtype of gastric cancer with the worst prognosis and few treatment options. Here we present a dataset from 84 DGC patients, composed of a proteome of 11,340 gene pr...
-
Article
Firmiana: towards a one-stop proteomic cloud platform for data processing and analysis
