35 Result(s)

Article

HSP90 Exacerbates Bone Destruction in Rheumatoid Arthritis by Activating TRAF6/NFATc1 Signaling

Rheumatoid arthritis (RA) is an autoimmune disease characterized by a notably high disability rate, primarily attributed to cartilage and bone degradation. The involvement of heat shock protein 90 (HSP90) as a...

Qian Wang, **angying Kong, Wanyi Guo, Liling Liu, Yage Tian, Xueying Tao… in Inflammation (2024)

Article

Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders

An imbalance of the tryptophan kynurenine pathway (KP) commonly occurs in psychiatric disorders, though the neurocognitive and network-level effects of this aberration are unclear.

Sugai Liang, Liansheng Zhao, Peiyan Ni, Qiang Wang, Wanjun Guo… in Psychopharmacology (2024)

Article

Shared and Distinct Topographic Alterations of Alpha-Range Resting EEG Activity in Schizophrenia, Bipolar Disorder, and Depression

Rui Xue, **ao**g Li, Jianning Chen, Sugai Liang, Hua Yu… in Neuroscience Bulletin (2023)

Article

Prognostic and Clinical Significance of Human Leukocyte Antigen Class I Expression in Breast Cancer: A Meta-Analysis

The value of human leukocyte antigen (HLA; also known as major histocompatibility complex) class I expression for the prediction of breast cancer survival outcomes remains unclear. We conducted a meta-analysis...

Weiqiang Qiao, Zhiqiang Jia, Wanying Guo, Qipeng Liu… in Molecular Diagnosis & Therapy (2023)

Article

Trajectories of α-fetoprotein and unresectable hepatocellular carcinoma outcomes receiving atezolizumab plus bevacizumab: a secondary analysis of IMbrave150 study

α-fetoprotein (AFP) response has been demonstrated as a biomarker for unresectable hepatocellular carcinoma (uHCC) patients receiving immunotherapy, but its definition is still unclear. This exploratory study ...

Linbin Lu, Peichan Zheng, Yan Pan, Shanshan Huang, Erqian Shao… in British Journal of Cancer (2023)

Article

The Brain Connectome for Chinese Reading

Chinese, as a logographic language, fundamentally differs from alphabetic languages like English. Previous neuroimaging studies have mainly focused on alphabetic languages, while the exploration of Chinese rea...

Wanwan Guo, Shujie Geng, Miao Cao, Jianfeng Feng in Neuroscience Bulletin (2022)

Article

Altered resting-state functional networks in patients with hemodialysis: a graph-theoretical based study

Recent studies have demonstrated that hemodialysis patients exhibit disruptions in functional networks with invisible cerebral alterations. We explored the alterations of functional connectivity in hemodialysi...

Mei **, Liyan Wang, Hao Wang, Xue Han, Zongli Diao, Wang Guo… in Brain Imaging and Behavior (2021)

Article

Cerebral blood flow alterations in hemodialysis patients with and without restless legs syndrome: an arterial spin labeling study

Hemodialysis with restless legs syndrome (HD-RLS) is associated with alterations in neuronal function, the blood-brain barrier and iron deposition, thus affecting cerebral metabolism and perfusion. This study ...

Hao Wang, Xue Han, Mei **, Li-yan Wang, Zong-li Diao… in Brain Imaging and Behavior (2021)

Article

Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips

The identification of prostate stem/progenitor cells and characterization of the prostate epithelial cell lineage hierarchy are critical for understanding prostate cancer initiation. Here, we characterized 35,...

Wangxin Guo, Lin Li, Juan He, Zhuang Liu, Ming Han, Fei Li, **nyi **a… in Nature Genetics (2020)

Article

GABAergic Abnormalities Associated with Sensorimotor Cortico-striatal Community Structural Deficits in ErbB4 Knockout Mice and First-Episode Treatment-Naïve Patients with Schizophrenia

The current study was designed to explore how disruption of specific molecular circuits in the cerebral cortex may cause sensorimotor cortico-striatal community structure deficits in both a mouse model and pat...

Chengcheng Zhang, Peiyan Ni, Yikang Liu, Yang Tian, **xue Wei… in Neuroscience Bulletin (2020)

Article

Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia

Liansheng Zhao, Huijuan Wang, Yamin Zhang, **xue Wei, Peiyan Ni… in Neuroscience Bulletin (2019)

Article

Age-Related Reduction in Cortical Thickness in First-Episode Treatment-Naïve Patients with Schizophrenia

Substantial evidence supports the neurodevelopmental hypothesis of schizophrenia. Meanwhile, progressive neurodegenerative processes have also been reported, leading to the hypothesis that neurodegeneration is...

Yin Lin, Mingli Li, Yi Zhou, Wei Deng, **aohong Ma, Qiang Wang… in Neuroscience Bulletin (2019)

Article

Genomic analyses in cotton identify signatures of selection and loci associated with fiber quality and yield traits

Tianzhen Zhang, **ongming Du and colleagues report whole-genome resequencing of 318 upland cotton (Gossypium hirsutum) accessions. They carried out genome-wide association analyses to identify loci associated wit...

Lei Fang, Qiong Wang, Yan Hu, Yinhua Jia, Jiedan Chen, Bingliang Liu… in Nature Genetics (2017)

Article

Heat shock protein 70 protects cardiomyocytes through suppressing SUMOylation and nucleus translocation of phosphorylated eukaryotic elongation factor 2 during myocardial ischemia and reperfusion

Myocardial ischemia and reperfusion (MIR) results in cardiomyocyte apoptosis with severe outcomes, which blocks cardiac tissue recovering from myocardial ischemia diseases. Heat shock protein 70 (HSP70) is one...

Chao Zhang, **aojuan Liu, ** Miao, Shengcun Wang, Liucheng Wu, Daliang Yan… in Apoptosis (2017)