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Open AccessUsing a longitudinal network structure to subgroup depressive symptoms among adolescents
Network modeling has been proposed as an effective approach to examine complex associations among antecedents, mediators and symptoms. This study aimed to investigate whether the severity of depressive symptom...
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Article
Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders
An imbalance of the tryptophan kynurenine pathway (KP) commonly occurs in psychiatric disorders, though the neurocognitive and network-level effects of this aberration are unclear.
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Shared and Distinct Topographic Alterations of Alpha-Range Resting EEG Activity in Schizophrenia, Bipolar Disorder, and Depression
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Article
Neural variability in three major psychiatric disorders
Across the major psychiatric disorders (MPDs), a shared disruption in brain physiology is suspected. Here we investigate the neural variability at rest, a well-established behavior-relevant marker of brain fun...
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Open AccessAssociation of elevated levels of peripheral complement components with cortical thinning and impaired logical memory in drug-naïve patients with first-episode schizophrenia
Schizophrenia has been linked to polymorphism in genes encoding components of the complement system, and hyperactive complement activity has been linked to immune dysfunction in schizophrenia patients. Whether...
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Open AccessAssociations between urban birth or childhood trauma and first-episode schizophrenia mediated by low IQ
Exposure to urban birth, childhood trauma, and lower Intelligence Quotient (IQ) were the most well-established risk factors for schizophrenia in developed countries. In develo** countries, whether urban birt...
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Open AccessRhein promotes the proliferation of keratinocytes by targeting oestrogen receptors for skin ulcer treatment
The Sheng-ji Hua-yu (SJHY) formula is a quite effective Traditional Chinese Medicines (TCM) in the treatment of delayed diabetic wounds. Previous research has shown that the SJHY formula has significant anti-i...
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Open AccessThe pattern glare and visual memory are disrupted in patients with major depressive disorder
Visual memory impairment is one of the most commonly complained symptoms in patients with major depressive disorder (MDD). Pattern glare is also a distorted visual phenomenon that puzzles patients with MDD. Ne...
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Open AccessComprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene
Identifying the causal genes at the risk loci and elucidating their roles in schizophrenia (SCZ) pathogenesis remain significant challenges. To explore risk variants associated with gene expression in the huma...
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Article
Sustained effects of left-behind experience during childhood on mental health in Chinese university undergraduates
Rapid industrialization and urbanization in China have resulted in labor migrants leaving children behind. For left-behind children (LBC), disrupted parental attachment may increase the risk of psychiatric mor...
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Open AccessTesting extra-linearity across a psychosis continuum
It is unclear whether psychotic experiences (PEs) gradually merge into states of clinical psychosis along a continuum which correspond to a dimensional classification or whether latent classes appear above a c...
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Open AccessImpact of urban birth and upbringing on expression of psychosis in a Chinese undergraduate population
Urban birth and upbringing show consistent associations with psychotic illness but the key urban exposures remain unknown. Associations with psychotic-like experiences (PEs) are inconsistent. These could be co...
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Article
Open AccessLower regional grey matter in alcohol use disorders: evidence from a voxel-based meta-analysis
Previous research using whole-brain neuroimaging techniques has revealed structural differences of grey matter (GM) in alcohol use disorder (AUD) patients. However, some of the findings diverge from other neur...
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Open AccessLasting effects of residential mobility during childhood on psychopathology among Chinese University students
Residential mobility during childhood increases risk of psychopathology in adulthood and is a common experience among Chinese children. This study investigated associations between number and age of first move...
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Correction: Functional brain networks in never-treated and treated long-term Ill schizophrenia patients
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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GABAergic Abnormalities Associated with Sensorimotor Cortico-striatal Community Structural Deficits in ErbB4 Knockout Mice and First-Episode Treatment-Naïve Patients with Schizophrenia
The current study was designed to explore how disruption of specific molecular circuits in the cerebral cortex may cause sensorimotor cortico-striatal community structure deficits in both a mouse model and pat...
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Open AccessHigh level of pattern glare in major depressive disorder
Visual deficits have been reported in abundance by recent studies on major depressive disorder. Pattern glare manifests as visual distortions, such as the symptoms of headache, glare, eyestrain, illusions of s...
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Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia
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Functional brain networks in never-treated and treated long-term Ill schizophrenia patients
This study compared the topological organization of brain function in never-treated and treated long-term schizophrenia patients. In a cross-sectional study, 21 never-treated schizophrenia patients with illnes...
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Age-Related Reduction in Cortical Thickness in First-Episode Treatment-Naïve Patients with Schizophrenia
Substantial evidence supports the neurodevelopmental hypothesis of schizophrenia. Meanwhile, progressive neurodegenerative processes have also been reported, leading to the hypothesis that neurodegeneration is...
