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  1. Article

    Abstracts

    Brian P. Kavanagh, Cuong Ngo, Karen Raymer, Homer Yang… in Canadian Journal of Anaesthesia (1997)

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    Chapter

    The Identification and Measurement in Urine of Dihydrodigoxin, a Cardioinactive Metabolite of Digoxin

    The sensitivity of an established mass spectroscopic technique has been improved in order to measure dihydrodigoxin, the cardioinactive metabolite of digoxin, in extracts of urine from paediatric patients main...

    H. Greenwood, W. Snedden in Mass Spectrometry in Drug Metabolism (1977)

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    Article

    Absolute identification of melatonin in human plasma and cerebrospinal fluid

    MELATONIN, the compound responsible for the lightening of amphibian skin, was extracted from bovine pineal glands and chemically characterised by Lerner et al.1,2. Recent reviews3–5 have suggested that melatonin ...

    IVOR SMITH, P. E. MULLEN, R. E. SILMAN, W. SNEDDEN, B. W. WILSON in Nature (1976)

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    Article

    A method for the measurement of ultra-low amounts of prostaglandins in inflammatory exudates using gas chromatography and mass spectrometry

    A GC-MS assay for PGE2 and PGF2α has been described. The method is highly specific and sensitive down to the sub-picogram level. The assay has been used to measure the time dependence of PG concentration in carra...

    B. W. Wilson, W. Snedden, K. T. Tham, D. A. Willoughby in Agents and Actions (1976)

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    Chapter

    A New Cause of Urinary Calculi: 2,8-Dihydroxyadenine Stones in Supposed ‘Uric Acid’ Crystalluria

    Most stones found in the human urinary tract are formed from common urinary constituents: calcium oxalate, calcium phosphate and ammonium magnesium phosphate. In situations of dehydration, aciduria or uric aci...

    H. A. Simmonds, K. J. Van Acker, J. S. Cameron, W. Snedden in Urolithiasis Research (1976)