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Chapter and Conference Paper
Glucocorticosteroid Treatment of Vasogenic Oedema
The components of vasogenic oedema associated with brain tumours were investigated in human biopsy material sampled from tumour and peritumoural tissue intraoperatively. Sixty patients with glioblastomas, glio...
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Chapter and Conference Paper
Regional Cerebral Protein Synthesis in Experimental Hydrocephalus
Hydrocephalic conditions have been studied extensively both in the clinic and in animal experiments. Most of these studies have dealt with the dynamics of cerebrospinal fluid and with the associated morphologi...
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Chapter and Conference Paper
Neurotransmitter Contents in Low-Grade Gliomas and Glioblastomas
Neurotransmitters in brain tumors have already been examined both experimentally and in vivo (2, 3, 4, 8). Up to now, concentrations of various neurotransmitters have received little attention when gliomas and gl...
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Chapter
Local Rates of Cerebral Protein Synthesis in the Gerbil and Monkey Brain
In autoradiographic studies of cerebral metabolism a radioactively labeled precursor is commonly used to trace the events of neurochemical reactions following brain uptake of the isotopic compound. Therefore, ...
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Chapter and Conference Paper
Selective Inhibition of Protein Synthesis After Severe Forebrain Ischemia of Gerbil Brain
The occurrence of selective vulnerability of distinct neuronal structures has been described in gerbil and rat brain [3, 4] following transient forebrain ischemia. Neither cerebral blood flow nor glucose utili...
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Chapter and Conference Paper
Quantitative Immunohistochemical Evaluation of Tumor Edema in Brain Tumors
The dynamic development of vasogenic brain edema is closely linked to the alterations of the brain tissue water content, the electrolyte concentration, and the extravasation of serum proteins. So far, quantita...
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Article
Relationship between specific gravity, water content, and serum protein extravasation in various types of vasogenic brain edema
Vasogenic brain edema was induced in cats by cold injury (six animals), brain tumors (five animals), and brain abscesses (six animals). Water and electrolyte content, specific gravity, blood volume, and the am...
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Chapter and Conference Paper
Regional Evaluation of Blood Flow and Metabolism in Experimental Brain Tumor of Rats
Development of brain tumors is associated with hemodynamic and metabolic disturbances of the brain, Partly because of local interference by tumor and peritumoral edema, and Partly because of general effects du...
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Chapter
Experimental Application of Triple-Labeled Quantitative Autoradiography for Measurement of Cerebral Blood Flow, Glucose Metabolism, and Protein Biosynthesis
During the past years autoradiographic techniques for measuring blood flow (Reivich et al. 1969; Sakurada et al. 1978) and metabolic activity (Sokoloff et al. 1977) have been of increasing interest in the stud...
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Chapter
Biochemical Prerequisites for Measurement of Protein Synthesis
One of the basic prerequisites for quantitative determination of cerebral metabolic rates of protein synthesis employing tracer quantities of radioactive-labeled amino acids is the measurement of the time-inte...
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Chapter and Conference Paper
Pathophysiological Aspects of Blood-Brain Barrier Disturbances in Experimental Brain Tumors and Brain Abscesses
According to the general neuropathological understanding, the breakdown of the blood-brain barrier results in the formation of vasogenic type of brain edema(1). In the early literature, vasogenic brain edema w...
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Article
Enzyme-immunoassay for the peptide hormone relaxin
The accuracy and sensitivity of the assay was found to reflect those of a radioimmunoassay procedure [2], Several advantages distinguish the relaxin EIA from the RIA, mainly the stability of the enzyme-labelle...
