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  1. Article

    Open Access

    A direct test of the diathesis–stress model for depression

    The diathesis–stress theory for depression states that the effects of stress on the depression risk are dependent on the diathesis or vulnerability, implying multiplicative interactive effects on the liability...

    L Colodro-Conde, B Couvy-Duchesne, G Zhu, W L Coventry, E M Byrne… in Molecular Psychiatry (2018)

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    Article

    Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

    The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with increased risk of depression, but only in individuals exposed to stressful situations, has generated mu...

    R C Culverhouse, N L Saccone, A C Horton, Y Ma, K J Anstey… in Molecular Psychiatry (2018)

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    Article

    Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

    Major depressive disorder (MDD) is a common complex trait with enormous public health significance. As part of the Genetic Association Information Network initiative of the US Foundation for the National Insti...

    P F Sullivan, E J C de Geus, G Willemsen, M R James, J H Smit… in Molecular Psychiatry (2009)

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    Article

    Perceived social support in a large community sample

    The positive health and wellbeing effects of social support have been consistently demonstrated in the literature since the late 1970s. However, a better understanding of the effects of age and sex is required.

    W. L. Coventry, N. A. Gillespie, A. C. Heath… in Social Psychiatry and Psychiatric Epidemio… (2004)