8 Result(s)

Article

A direct test of the diathesis–stress model for depression

The diathesis–stress theory for depression states that the effects of stress on the depression risk are dependent on the diathesis or vulnerability, implying multiplicative interactive effects on the liability...

L Colodro-Conde, B Couvy-Duchesne, G Zhu, W L Coventry, E M Byrne… in Molecular Psychiatry (2018)

Article

Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades. Here we present the largest ever worldwide study b...

L Schmaal, D P Hibar, P G Sämann, G B Hall, B T Baune, N Jahanshad… in Molecular Psychiatry (2017)

Article

Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group

The aetiology of suicidal behaviour is complex, and knowledge about its neurobiological mechanisms is limited. Neuroimaging methods provide a noninvasive approach to explore the neural correlates of suicide vu...

M E Rentería, L Schmaal, D P Hibar, B Couvy-Duchesne… in Translational Psychiatry (2017)

Article

Genetic effects influencing risk for major depressive disorder in China and Europe

Major depressive disorder (MDD) is a common, complex psychiatric disorder and a leading cause of disability worldwide. Despite twin studies indicating its modest heritability (~30–40%), extensive heterogeneity...

T B Bigdeli, S Ripke, R E Peterson, M Trzaskowski, S-A Bacanu… in Translational Psychiatry (2017)

Article

Erratum: Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

Correction to: Molecular Psychiatry 21, 749–757; doi:10.1038/mp.2016.49 The GWAS of neuroticism conducted within the Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute cohort ...

D J Smith, V Escott-Price, G Davies, M E S Bailey, L Colodro-Conde… in Molecular Psychiatry (2016)

Article

Response to Dr Fried & Dr Kievit, and Dr Malhi et al.

L Schmaal, D J Veltman, T G M van Erp, P G Sämann, T Frodl… in Molecular Psychiatry (2016)

Article

Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

Neuroticism is a personality trait of fundamental importance for psychological well-being and public health. It is strongly associated with major depressive disorder (MDD) and several other psychiatric conditi...

D J Smith, V Escott-Price, G Davies, M E S Bailey, L Colodro-Conde… in Molecular Psychiatry (2016)

Article

Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

The pattern of structural brain alterations associated with major depressive disorder (MDD) remains unresolved. This is in part due to small sample sizes of neuroimaging studies resulting in limited statistica...

L Schmaal, D J Veltman, T G M van Erp, P G Sämann, T Frodl… in Molecular Psychiatry (2016)