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    Article

    Indole-3-acetic acid correlates with monocyte-to-high-density lipoprotein (HDL) ratio (MHR) in chronic kidney disease patients

    Indole-3-acetic acid is a protein-bound indolic uremic toxin deriving from tryptophan metabolism. Increased levels are associated with higher thrombotic risk and both cardiovascular and all-cause mortality. An...

    Valeria Cernaro, Vincenzo Calabrese, Saverio Loddo… in International Urology and Nephrology (2022)

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    Article

    RAS inhibition modulates kynurenine levels in a CKD population with and without type 2 diabetes mellitus

    Kynurenine pathway of tryptophan metabolism is involved in the pathophysiology of chronic kidney disease (CKD) and diabetes mellitus, mainly through the inflammation-induced activity of indoleamine 2,3-dioxyge...

    Valeria Cernaro, Saverio Loddo, Vincenzo Macaione… in International Urology and Nephrology (2020)