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Article
Open AccessPlasma essential fatty acid on hospital admission is a marker of COVID-19 disease severity
It is important for allocation of resources to predict those COVID patients at high risk of dying or organ failure. Early signals to initiate cellular events of host immunity can be derived from essential fatt...
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Article
Open AccessDepletion of essential fatty acids in muscle is associated with shorter survival of cancer patients undergoing surgery-preliminary report
Emerging studies are reporting associations between skeletal muscle abnormalities and survival in cancer patients. Cancer prognosis is associated with depletion of essential fatty acids in erythrocytes and pla...
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Article
Open AccessSarcopenia in cirrhosis: from pathogenesis to interventions
Sarcopenia (severe muscle depletion) is a prevalent muscle abnormality in patients with cirrhosis that confers poor prognosis both pre- and post-liver transplantation. The pathogenesis of sarcopenia is multifa...
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Article
Open AccessImmunohistochemical phenoty** of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression
Inflammation is a recognized contributor to muscle wasting. Research in injury and myopathy suggests that interactions between the skeletal muscle and immune cells confer a pro-inflammatory environment that in...
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Article
Sensory preferences of supplemented food products among cancer patients: a systematic review
Oral nutritional supplements and fortified foods, here considered supplemented food products (SFP), are recommended as part of nutrition therapy guidelines to treat malnutrition among cancer patients. However,...
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Article
Open AccessA quantitative multimodal metabolomic assay for colorectal cancer
Early diagnosis of colorectal cancer (CRC) simplifies treatment and improves treatment outcomes. We previously described a diagnostic metabolomic biomarker derived from semi-quantitative gas chromatography-mas...
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Article
Open AccessChemotherapy diminishes lipid storage capacity of adipose tissue in a preclinical model of colon cancer
Accelerated loss of adipose tissue in cancer is associated with shorter survival, and reduced quality of life. Evidence is emerging suggesting tumour association with alterations in adipose tissue, but much le...
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Article
Open AccessSubcutaneous adiposity is an independent predictor of mortality in cancer patients
Prognostic significance of adiposity, at the time of cancer diagnosis, on survival is not clear. Body mass index (kg m−2) does not provide an appropriate assessment of body composition; therefore, the concept of ...
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Article
Clinical Implications of Sarcopenic Obesity in Cancer
Sarcopenia has been associated with several negative clinical outcomes in cancer. However, the consequences of sarcopenic obesity, a condition of combined sarcopenia and obesity burden, have been less extensiv...
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Article
N-3 Polyunsaturated Fatty Acids: Relationship to Inflammation in Healthy Adults and Adults Exhibiting Features of Metabolic Syndrome
Individuals with metabolic syndrome (MetS) have a higher risk of type 2 diabetes and cardiovascular disease, therefore, research has been directed at reducing various components that contribute to MetS and ass...
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Article
Aberrations in Plasma Phospholipid Fatty Acids in Lung Cancer Patients
Abnormalities in lipid metabolism have been frequently observed in cancer and are associated with a poor prognosis. However, a detailed, longitudinal characterization of fatty acid status is lacking. This stud...
