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  1. Article

    Open Access

    Comprehensive analysis of clinical outcomes, infectious complications and microbiological data in newly diagnosed multiple myeloma patients: a retrospective observational study of 92 subjects

    Patients with multiple myeloma (MM) have an increased risk of sepsis due to underlying disease- and treatment-related immunosuppression. However, data on sepsis incidence, causative pathogens, and impact on ou...

    Vanessa Desantis, Paola Borrelli, Teresa Panebianco in Clinical and Experimental Medicine (2024)

  2. Article

    Open Access

    STAT1 overexpression triggers aplastic anemia: a pilot study unravelling novel pathogenetic insights in bone marrow failure

    We identified STAT1 gain of function (GOF) in a 32-year-old female with pallor, weakness, cough, and dyspnea admitted to our Division of Medicine. She had severe oral ulcers (OU), type 1 diabetes (T1DM), and p...

    Antonio Giovanni Solimando, Vanessa Desantis in Clinical and Experimental Medicine (2023)

  3. Article

    Open Access

    Immune disturbance leads to pulmonary embolism in COVID-19 more than classical risk factors: a clinical and histological study

    COVID-19 induces endotheliitis and one of the main complications is enhanced coagulation. The incidence of pulmonary embolism (PE) in COVID-19 (CPE) has increased and clinical features for a rigorous analysis ...

    Sebastiano Cicco, Antonio Vacca, Federica Albanese in Internal and Emergency Medicine (2023)

  4. No Access

    Protocol

    Visualizing the Interactions Sha** the Imaging of the Microenvironment in Human Cancers

    The Visium Spatial Gene Expression Solution (Visium 10×) allows for the mRNA analysis using high throughput sequencing and maps a transcriptional expression pattern in tissue sections using high-resolution mic...

    Antonio G. Solimando, Vanessa Desantis, Matteo Claudio Da Vià in Tumor Angiogenesis Assays (2023)

  5. No Access

    Article

    Rhu-Epo down-regulates pro-tumorigenic activity of cancer-associated fibroblasts in multiple myeloma

    We have previously demonstrated that recombinant human erythropoietin (rHuEpo) is involved in the regulation of the angiogenic response in multiple myeloma (MM) through a direct effect on macrophages and endot...

    Vanessa Desantis, Maria Antonia Frassanito, Roberto Tamma in Annals of Hematology (2018)