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Article
Open AccessForming cytoplasmic stress granules PURα suppresses mRNA translation initiation of IGFBP3 to promote esophageal squamous cell carcinoma progression
Esophageal squamous cell carcinoma (ESCC) is one of the most fatal malignancies worldwide. Recently, our group identified purine-rich element binding protein alpha (PURα), a single-stranded DNA/RNA-binding pro...
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Article
Open AccessDownregulation of Zn-transporters along with Fe and redox imbalance causes growth and photosynthetic disturbance in Zn-deficient tomato
Zinc (Zn) deficiency hinders growth and development in tomato. This study unveils the responses of how Zn starvation affects physiological and molecular processes in tomato. Zn deficiency negatively affected t...
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Interplay Between Environmental Signals and Endogenous Salicylic Acid
Salicylic acid (SA), a naturally occurring growth regulator and signaling molecule plays critical roles in the growth and development of plants along with stress tolerance. Most of the synthesized SA is glucos...
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Article
Mitigation of Chromium Toxicity in Wheat (Triticum aestivum L.) Through Silicon
Chromium (Cr) is a toxic metal usually found in soil and water, causing environmental pollution. Silicon (Si), however, has excelled in alleviating the stress caused by toxic elements in plants, and its benefi...
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Article
Arbuscular mycorrhizal fungi mitigate Fe deficiency symptoms in sorghum through phytosiderophore-mediated Fe mobilization and restoration of redox status
Sustainable management of iron (Fe) deficiency through the microbial association is highly desirable to ensure crop yield. This study elucidates whether and how arbuscular mycorrhizal fungi (AMF) ameliorate Fe...
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Article
The Challenges of Cortisol Replacement Therapy in Childhood: Observations from a Case Series of Children Treated with Modified-Release Hydrocortisone
Hydrocortisone is the preferred treatment for adrenal insufficiency in childhood. A small minority of children experience low cortisol concentrations and symptoms of cortisol insufficiency, poorly responsive t...
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Article
Open AccessMode of clinical presentation and delayed diagnosis of Turner syndrome: a single Centre UK study
Early diagnosis of girls with Turner syndrome (TS) is essential to provide timely intervention and support. The screening guidelines for TS suggest karyotype evaluation in patients presenting with short statur...
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Menstrual Disorders and Vaginal Discharge
Disorders of menstruation in adolescents are the second most common symptom group after vulvovaginitis and pelvic discharge referred to the paediatric and adolescent gynaecology service. In general, menstrual ...