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  1. Article

    Open Access

    Nicotinic receptors mediate stress-nicotine detrimental interplay via dopamine cells’ activity

    Epidemiological studies report strong association between mood disorders and tobacco addiction. This high comorbidity requires adequate treatment but the underlying mechanisms are unknown. We demonstrate that ...

    C Morel, S P Fernandez, F Pantouli, F J Meye, F Marti, S Tolu… in Molecular Psychiatry (2018)

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  2. Article

    Open Access

    GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons

    Human mutations of the GRID1 gene encoding the orphan delta1 glutamate receptor-channel (GluD1) are associated with schizophrenia but the explicit role of GluD1 in brain circuits is unknown. Based on the known fu...

    N Benamer, F Marti, R Lujan, R Hepp, T G Aubier, A A M Dupin… in Molecular Psychiatry (2018)

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  3. No Access

    Article

    Nicotine consumption is regulated by a human polymorphism in dopamine neurons

    Smoking is the most important preventable cause of morbidity and mortality worldwide. Recent genome-wide association studies highlighted a human haplotype on chromosome 15 underlying the risk for tobacco depen...

    C Morel, L Fattore, S Pons, Y A Hay, F Marti, B Lambolez… in Molecular Psychiatry (2014)

  4. No Access

    Article

    Disinhibition goes up in smoke

    F Marti, U Maskos, P Faure in Molecular Psychiatry (2013)

  5. No Access

    Article

    Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement

    Smoking is the most important preventable cause of mortality and morbidity worldwide. This nicotine addiction is mediated through the nicotinic acetylcholine receptor (nAChR), expressed on most neurons, and al...

    S Tolu, R Eddine, F Marti, V David, M Graupner, S Pons, M Baudonnat… in Molecular Psychiatry (2013)

  6. No Access

    Article

    Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors

    B. E. Molles, U. Maskos, S. Pons, M. Besson… in Journal of Molecular Neuroscience (2006)

  7. No Access

    Article

    Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

    The bad news, nicotine addiction has caused the deaths of millions from smoking-related diseases. The good news, nicotine can enhance cognitive performance. In an attempt to disentangle the brain networks that...

    U. Maskos, B. E. Molles, S. Pons, M. Besson, B. P. Guiard, J.-P. Guilloux… in Nature (2005)