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  1. Article

    Open Access

    Towards a Large-Scale Assessment of the Relationship Between Biological and Chronological Aging: The Inspire Mouse Cohort

    Aging is the major risk factor for the development of chronic diseases. After decades of research focused on extending lifespan, current efforts seek primarily to promote healthy aging. Recent advances suggest...

    Y. Santin, S. Lopez, I. Ader, S. Andrieu, N. Blanchard… in The Journal of Frailty & Aging (2021)

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  2. Article

    Open Access

    BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities

    The therapeutic activity of selective serotonin (5-HT) reuptake inhibitors (SSRIs) relies on long-term adaptation at pre- and post-synaptic levels. The sustained administration of SSRIs increases the serotoner...

    G Quesseveur, D J David, M C Gaillard, P Pla, M V Wu… in Translational Psychiatry (2013)

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  3. No Access

    Article

    5-HT2A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system

    Evidence suggests that the serotonin 2A receptor (5-HT2AR) modulates the therapeutic activity of selective serotonin reuptake inhibitors (SSRIs). Indeed, among the genetic factors known to influence the individua...

    G. Quesseveur, C. Repérant, D. J. David, A. M. Gardier… in Experimental Brain Research (2013)

  4. No Access

    Article

    Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors

    B. E. Molles, U. Maskos, S. Pons, M. Besson… in Journal of Molecular Neuroscience (2006)

  5. No Access

    Article

    Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

    The bad news, nicotine addiction has caused the deaths of millions from smoking-related diseases. The good news, nicotine can enhance cognitive performance. In an attempt to disentangle the brain networks that...

    U. Maskos, B. E. Molles, S. Pons, M. Besson, B. P. Guiard, J.-P. Guilloux… in Nature (2005)