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  1. Article

    Open Access

    MR-guided adaptive stereotactic body radiotherapy (SBRT) of primary tumor for pain control in metastatic pancreatic ductal adenocarcinoma (mPDAC): an open randomized, multicentric, parallel group clinical trial (MASPAC)

    Pain symptoms in the upper abdomen and back are prevalent in 80% of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC), where the current standard treatment is a systemic therapy consisting of a...

    M. Pavic, M. Niyazi, L. Wilke, S. Corradini, M. Vornhülz, U. Mansmann… in Radiation Oncology (2022)

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  2. No Access

    Article

    Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark

    Rheumatische Erkrankungen gehören zu den häufigsten chronisch entzündlichen Krankheiten. Neben ausgeprägter Schmerzhaftigkeit und progredienter Gelenkzerstörung reduzieren die rheumatoide Arthritis (RA), die S...

    PD Dr. T. Häupl, A. Skapenko, B. Hoppe, K. Skriner… in Zeitschrift für Rheumatologie (2018)

  3. Article

    Open Access

    Immunological profiling of patients with ulcerative colitis leads to identification of two inflammatory conditions and CD1a as a disease marker

    Conventional approaches to understand mechanisms underlying the development of pathological manifestations in ulcerative colitis (UC) mostly rely on identification of certain cell types and cytokines followed ...

    M. Föhlinger, P. Palamides, U. Mansmann, F. Beigel… in Journal of Translational Medicine (2016)

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  4. Article

    Erratum zu: Therapie asymptomatischer Karotisstenosen. Notwendige Klärung der Evidenz mit neuem SPACE-2-Design

    Dr. T. Reiff, H. Amiri, G. Fraedrich, O. Jansen, H. Mudra, U. Mansmann… in Gefässchirurgie (2014)

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  5. Article

    Erratum zu: Therapie asymptomatischer Karotisstenosen

    Dr. T. Reiff, H. Amiri, G. Fraedrich, O. Jansen, H. Mudra, U. Mansmann… in Der Nervenarzt (2014)

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  6. Article

    Open Access

    EGFR pathway biomarkers in erlotinib-treated patients with advanced pancreatic cancer: translational results from the randomised, crossover phase 3 trial AIO-PK0104

    We aimed to identify molecular epidermal growth factor receptor (EGFR) tissue biomarkers in pancreatic cancer (PC) patients treated with the anti-EGFR agent erlotinib within the phase 3 randomised AIO-PK0104 s...

    S Boeck, A Jung, R P Laubender, J Neumann, R Egg, C Goritschan… in British Journal of Cancer (2013)

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  7. No Access

    Article

    An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia

    T Herold, V Jurinovic, K H Metzeler, A-L Boulesteix, M Bergmann, T Seiler… in Leukemia (2011)

  8. No Access

    Article

    Klinische Merkmale, Progression und Risikofaktoren bei geographischer Atrophie

    Die geographische Atrophie (GA) als Spätmanifestationsform der trockenen altersabhängigen Makuladegeneration (AMD) ist eine progrediente Erkrankung, bei der es zur Atrophie des retinalen Pigmentepithels, der k...

    Dr. C.K. Brinkmann, C. Adrion, U. Mansmann, S. Schmitz-Valckenberg… in Der Ophthalmologe (2010)

  9. Article

    Insulin resistance and increased risk for malignant neoplasms: confounding of the data on insulin glargine

    J. M. Nagel, U. Mansmann, K. Wegscheider, J. Röhmel in Diabetologia (2010)

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  10. No Access

    Chapter and Conference Paper

    Correlation of molecular profiles and clinical course of stage II colon cancer patients

    Up to 25% of all resected patients with localized colon cancer (stage UICCII) develop recurrence and die from the disease within 5 years. The aim of the study was to identify and validate a microarray-based pr...

    Dr. med. J. Gröne, D. Lenze, H. Seidel… in Chirurgisches Forum und DGAV Forum 2009 (2009)

  11. No Access

    Article

    Risk of advanced metachronous colorectal adenoma during long-term follow-up

    According to the adenoma–carcinoma concept, all colorectal adenomas are to be removed and all patients have to undergo regular surveillance examinations. But there is still shortage on information on the long-...

    G. Nusko, E. G. Hahn, U. Mansmann in International Journal of Colorectal Disease (2008)

  12. No Access

    Article

    Gene expression in human peripheral blood mononuclear cells upon acute ischemic stroke

    Ischemic stroke provokes a systemic inflammatory response. The purpose of this study was to characterize this response on the gene expression level in circulating mononuclear leukocytes from acute ischemic str...

    Dr. C. Grond-Ginsbach, M. Hummel, T. Wiest, S. Horstmann… in Journal of Neurology (2008)

  13. Article

    GERAC-Studie zu Akupunktur bei Gonarthrose

    Akupunktur erfreut sich zunehmender Beliebtheit in der Therapie chronischer Knieschmerzen. Allerdings wurde bis vor kurzem die Evidenz der klinischen Akupunkturwirksamkeit als unzureichend für eine Integration...

    Dr. K. Streitberger, U. Mansmann, N. Victor in Trauma und Berufskrankheit (2007)

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  14. No Access

    Article

    Follow-up after colorectal polypectomy: a benefit–risk analysis of German surveillance recommendations

    For colorectal screening patients a mean gain of life time was previously calculated of about 30–50 days. Different recommendations for recognising at-risk groups and defining surveillance intervals after an i...

    F. Becker, G. Nusko, J. Welke, E. G. Hahn… in International Journal of Colorectal Disease (2007)

  15. Article

    Open Access

    Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma – CapRI: study protocol [ISRCTN62866759]

    After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-yea...

    HP Knaebel, A Märten, J Schmidt, K Hoffmann, C Seiler, K Lindel… in BMC Cancer (2005)

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  16. Article

    Open Access

    Automated analysis of digital fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration using confocal scanning laser ophthalmoscopy (cSLO)

    Fundus autofluorescence (AF) imaging using confocal scanning laser ophthalmoscopy (cSLO) provides an accurate delineation of areas of geographic atrophy (GA).

    A Deckert, S Schmitz-Valckenberg, J Jorzik, A Bindewald, FG Holz… in BMC Ophthalmology (2005)

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  17. No Access

    Article

    Prognoserelevanz von biologischen und molekularen Markern in der Onkologie

    E. Bollschweiler, P.M. Schneider, S.P. Mönig, A. Altendorf-Hofmann… in Der Chirurg (2003)

  18. No Access

    Article

    Effect of Partial Targeted N-Butyl-Cyano-Acrylate Embolization in Brain AVM

    H. J. Meisel, U. Mansmann, H. Alvarez, G. Rodesch, M. Brock… in Acta Neurochirurgica (2002)

  19. No Access

    Article

    The prognostic inhomogeneity in pT3 rectal carcinomas

    To obtain data on locoregional recurrence and survival rates in prognostically inhomogeneous pT3 rectal carcinomas we analyzed the data on 853 patients of the Erlangen Registry for Colo-Rectal Carcinomas (ERC...

    S. Merkel, U. Mansmann, M. Siassi… in International Journal of Colorectal Disease (2001)

  20. No Access

    Article

    Concepts and Data Model for a Co-Operative Neurovascular Database

    U. Mansmann, W. Taylor, P. Porter, J. Bernarding, H. R. Jäger… in Acta Neurochirurgica (2001)

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