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Article
Conjunctival polyploid cells and donor-derived myofibroblasts in ocular GvHD
After allogeneic hematopoietic stem cell transplantation (allo-SCT), ocular GvHD is a common complication, typical symptoms being dry eye syndrome with features of fibrosis. In this study, we have identified a...
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Article
Synthesis of hyaluronan by normal and wounded rabbit iris
Background: Endogenous hyaluronan has been found in different tissues in the normal and traumatized eye. However, the main source, the biological aspects and the full potential role of hyloronan are still unclea...
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Chapter
Behavioural Compensation after Dopamine Grafts in Brain
For almost a century attempts have been made to transplant neuronal tissue to the central nervous system of mammals. The conditions for attaining reliable graft survival have now been characterised and the tra...
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Article
Anatomical and functional consequences of grafting mesencephalic neurons into a peripheral nerve “bridge” connected to the denervated striatum
Adult rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway were tested for amphetamine-induced rotational asymmetry. In animals with functional deficits a fetal mesencephalic transplant ...
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Article
Functional reactivation of the deafferented hippocampus by embryonic septal grafts as assessed by measurements of local glucose utilization
Transection of the septo-hippocampal connections through fimbria-fornix damage in the rat results in profound hippocampal cholinergic deafferentation, and, when applied bilaterally, leads to severe and long-la...
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Chapter and Conference Paper
Transplant-Induced Recovery from Brain Lesions: A Review of the Nigrostriatal Model
The past decade has seen rapid advances in the development of techniques for the transplantation of central nervous tissue. Today, good survival of grafted tissue can be achieved, and the establishment of reci...
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Article
A model for xenotransplantation of human malignant astrocytomas into the brain of normal adult rats
Transplantation of human brain tumours into the brain of normal laboratory animals is still considered to be unsatisfactory by many researchers, despite the fact that the brain is considered an immunologically...
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Article
Functional reactivation of the deafferented neostriatum by nigral transplants
Functional deficits following brain lesions can be due not only to the disruption of conduction in specific input and output pathways passing through the site of injury, but also to the loss of important regul...
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Article
The use of neurotoxic dihydroxytryptamines as tools for morphological studies and localized lesioning of central indolamine neurons
The usefulness of three neurotoxic dihydroxytryptamines — 5,6-dihydroxytryptamine, 5,7-dihydroxytryptamine and 4,5-dihydroxytryptamine — for fluorescence microscopical tracing and localized lesioning of centra...
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Article
Adrenergic and non-adrenergic valvular nerves of the heart
Toutes les valvules du rat, sauf une valvule de l'aorte, contiennent des nerfs adrénergique et cholinergique. Très souvent, les deux types d'axones courent très près l'un de l'autre comme ceux de l'iris du rat.