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Article
Mediated exodus of L-dopa from human epidermal Langerhans cells
L-3,4-dihydroxyphenylalanine (L-dopa) is not metabolized within human epidermal Langerhans cells (LC); yet they can take up substantial amounts of this amino acid which subsequently can be released into the ex...
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Article
Lysosomotropic agents activate the capacity for calcium dependent pinocytosis in starvedAmoeba proteus: evidence for a mechanism involving phospholipase A2
Pinocytosis induced by Na+ was assayed by phase contrast microscopy in 8–12 days starvedAmoeba proteus. These cultures were inactive with respect to calcium-dependent Na+-induced pinocytosis, but treatment with a...
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Article
Distributional changes of Langerhans cells in human skin during irritant contact dermatitis
We used light and electron microscopic immunocytochemistry to study distributional changes in the human Langerhans cell (LC) system during the first 14 days of a mild irritancy caused by sodium lauryl sulphate...
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Article
New approaches to motor unit potential analysis
The current state of motor unit potential (MUP) analysis is reviewed. New quantitative analysis methods are described and compared with traditional manual measurements. The emphasis in this review is on a new ...
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Article
Muscle pathology in idiopathic cricopharyngeal dysphagia
The structural changes in the cricopharyngeal muscle (CM) were examined ultrastructurally and by enzyme histochemistry in five patients suffering from idiopathic cricopharyngeal dysphagia (ICD). Diagnosis was ...
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Article
New fluorophore-forming reactions for histochemical visualization of N-acetylated and tertiary indolamines using glyoxylic acid, aluminum-formaldehyde and trifluoroacetic acid anhydride as reagents
N-acetylated and tertiary indolamines, some of which are possible neurotransmitter candidates in the CNS, cannot be visualized with the standard Falck-Hillarp histofluorescence method and very little is known ...
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Article
The firing rate of motor units in neuromuscular disorders
The firing frequency and interval variability of motor units was studied in healthy controls and in patients suffering from peripheral neuromuscular disorders. In patients with myopathic disorders, the motor u...
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Article
A two-channel method for sampling, averaging and quantifying motor unit potentials
A method is described for sampling and averaging individual motor unit potentials (MUPs), which is based on an averaging technique using a special EMG electrode. The needle has two separate electrode surfaces,...
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Article
New aspects on factors determining the sensitivity of the formaldehyde and glyoxylic acid fluorescence histochemical methods for monoamines
The fluorophore and fluorescence yield from tryptamine and 3-methoxytyramine in histochemical protein models have been compared in the standard formaldehyde reaction, the acid-catalyzed formaldehyde reaction, ...
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Article
Application of the aluminum-formaldehyde (ALFA) histofluorescence method for demonstration of peripheral stores of catecholamines and indolamines in freeze-dried paraffin-embedded tissue, cryostat sections and whole-mounts
This paper describes new procedures for highly sensitive visualization of monoamine stores in peripheral tissues, taking advantage of the recently introduced aluminum-catalysed formaldehyde (ALFA) reaction. Th...
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Article
Organization of the sympathetic innervation in liver tissue from monkey and man
The sympathetic innervation of the liver of monkey and man has been investigated in a combined fluorescence histochemical, chemical and electron microscopical study. By means of the Falck-Hillarp fluorescence ...
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Article
Evidence for new catecholamines or related amino acids in some invertebrate sensory neurons
In certain sensory neurons of many different invertebrate species, including the sea anemones. Metridium senile and Tealia felina and the crustacean Anemia salina, fluorophores are formed during the course of the...
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Article
Innervation of iridic melanophores
The nerve supply to the iridic melanophores of the rat was studied with the electron microscope. The adrenergic and cholinergic terminals were identified with the aid of 5-hydroxydopamine, which produces dense...
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Article
Adrenergic neurons in the spinal cord of the pike (Esox lucius) and their relation to the caudal neurosecretory system
The lower spinal cord including the caudal neurosecretory system of the pike (Esox lucius) was investigated by means of light and electron microscopy and also with the fluorescence histochemical method of Falck a...
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Article
Possible axo-axonal synapses between peripheral adrenergic and cholinergic nerve terminals
The relations between adrenergic and cholinergic terminals were studied in rat iris and rat heart with the electron microscope. Adrenergic terminals were identified by treating the animals with 5-hydroxydopami...
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Article
Morphological and pharmacohistochemical characteristics of adrenergic retinal neurons of some mammals
The adrenergic retinal neurons were studied in cynomolgus and squirrel monkeys, cats, rabbits, guinea-pigs, rats and mice. In addition to what has previously been described, some very few adrenergic terminals ...
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Article
Adrenergic retinal neurons of some new world monkeys
The retina of Aotes monkeys, Cebus monkeys, squirrel monkeys, and marmosets were investigated. Adrenergic perikarya were found in the innermost cell rows of the inner nuclear layer of all the investigated spec...
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Article
Adrenergic nerves to the dermal melanophores of the rainbow trout, Salmo Gairdneri
The stellate processes and cell bodies of the dermal melanophores in the rainbow trout are intimately enclosed by a plexus of thin varicose nerves which display a specific catecholamine fluorescence. The nerve...
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Article
Adrenergic denervation of the eye by unilateral cervical sympathectomy
The adrenergic innervation of the eye of rabbits, rats, guinea-pigs, cats, and goats were studied with chemical estimates of noradrenaline and fluorescence microscopical demonstration of adrenergic fibres afte...
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Article
Dopa-decarboxylase and monoamine oxidase activities in a transplantable islet cell tumour of the golden hamster
In einem transplantierbaren Inselzelltumor des Goldhamsters, der neben 5-Hydroxytryptamin, Dopa und Dopamin eine bisher unidentifizierte, vermutlich monoaminähnliche Substanz enthält, wurde eine hohe Dopadecar...
