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Article
Perspective: use and reuse of NMR-based metabolomics data: what works and what remains challenging
The National Cancer Institute issued a Request for Information (RFI; NOT-CA-23-007) in October 2022, soliciting input on using and reusing metabolomics data. This RFI aimed to gather input on best practices fo...
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Article
Open AccessEstablishing a framework for best practices for quality assurance and quality control in untargeted metabolomics
Quality assurance (QA) and quality control (QC) practices are key tenets that facilitate study and data quality across all applications of untargeted metabolomics. These important practices will strengthen thi...
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Article
Multi-omics characterization of NIST seafood reference materials and alternative matrix preparations
The National Institute of Standards and Technology (NIST) has prepared four seafood reference materials (RMs) for use in food safety and nutrition studies: wild-caught and aquacultured salmon (RM 8256 and RM 8...
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Article
Open AccessReference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC)
The metabolomics quality assurance and quality control consortium (mQACC) is enabling the identification, development, prioritization, and promotion of suitable reference materials (RMs) to be used in quality ...
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Article
Identifying metabolic alterations associated with coral growth anomalies using 1H NMR metabolomics
Coral growth anomalies (GAs) are tumor-like protrusions that are detrimental to coral health, affecting both the coral skeleton and soft tissues. These lesions are increasingly found throughout the tropics and...
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Article
Open AccessMorphological, elemental, and boron isotopic insights into pathophysiology of diseased coral growth anomalies
Coral growth anomalies (GAs) are tumor-like lesions that are detrimental to colony fitness and are commonly associated with high human population density, yet little is known about the disease pathology or cal...
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Article
Rapid and reliable steroid hormone profiling in Tursiops truncatus blubber using liquid chromatography tandem mass spectrometry (LC-MS/MS)
Monitoring of marine mammal steroid hormone status using matrices alternative to blood is desirable due to the ability to remotely collect samples, which minimizes stress to the animal. However, measurement te...
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Article
Open AccessEffects of heat-treatment on the stability and composition of metabolomic extracts from the earthworm Eisenia fetida
Environmental metabolomics studies employing earthworms as sentinels for soil contamination are numerous, but the instability of the metabolite extracts from these organisms has been minimally addressed. This ...
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Article
Open AccessApplication of NMR-based metabolomics for environmental assessment in the Great Lakes using zebra mussel (Dreissena polymorpha)
Zebra mussel, Dreissena polymorpha, in the Great Lakes is being monitored as a bio-indicator organism for environmental health effects by the National Oceanic and Atmospheric Administration’s Mussel Watch progra...
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Article
Metabolomic analysis of Atlantic blue crab, Callinectes sapidus, hemolymph following oxidative stress
The Atlantic blue crab, Callinectes sapidus, is an economically, ecologically, and recreationally valuable decapod crustacean that inhabits estuaries along the Atlantic and Gulf coasts of the United States. In th...
