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  1. Article

    Open Access

    Onionin A inhibits small-cell lung cancer proliferation through suppressing STAT3 activation induced by macrophages-derived IL-6 and cell–cell interaction with tumor-associated macrophage

    Tumor-associated macrophage (TAM)-derived IL-6 is involved in small-cell lung cancer (SCLC) progression and chemoresistance via the activation of signal transducer and activator of transcription 3 (STAT3) in t...

    Remi Mito, Toyohisa Iriki, Yukio Fujiwara, Cheng Pan, Tsuyoshi Ikeda… in Human Cell (2023)

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    Article

    Cyclic sulfur compounds targeting macrophage polarization into M2/protumor phenotype and their anti-tumor effects

    Tumor-associated macrophages (TAMs), especially the M2-like phenotype, promote tumor progression, making them candidate targets for anti-tumor therapy. We previously discovered a cyclic sulfur compound, Onioni...

    Cheng Pan, Yukio Fujiwara, Hasita Horlad… in Cancer Immunology, Immunotherapy (2022)

  3. Article

    Chemotherapy for thymic carcinoma in an adult patient with HIV infection

    A 69-year-old man was referred to our hospital in June 2010 after the diagnosis of an anterior mediastinal tumor and HIV infection. Histopathological examination of a CT-guided needle biopsy specimen showed un...

    Toyohisa Iriki, Satoru Ishii, Yuichiro Takeda… in International Cancer Conference Journal (2012)

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