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Article
Publisher Correction: Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis
Change history: In this Letter, the bottom blot in Fig. 2g (for ‘IB: Myc’) was missing. This has been corrected online.
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Article
Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis
Ribosome-associated quality control (RQC) provides a rescue pathway for eukaryotic cells to process faulty proteins after translational stalling of cytoplasmic ribosomes1–6. After dissociation of ribosomes, the s...
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Protocol
Isolation of Mitochondria from Saccharomyces cerevisiae
The budding yeast Saccharomyces cerevisiae is an important model organism to study cellular structure and function. Due to its excellent accessibility to genetics and biochemical and microscopic analyses, studies...
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Article
Open AccessQuality control of nonstop membrane proteins at the ER membrane and in the cytosol
Since messenger RNAs without a stop codon (nonstop mRNAs) for organelle-targeted proteins and their translation products (nonstop proteins) generate clogged translocon channels as well as stalled ribosomes, ce...
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Article
Decrease in cytosine methylation at CpG island shores and increase in DNA fragmentation during zebrafish aging
Age-related changes in DNA methylation have been demonstrated in mammals, but it remains unclear as to the generality of this phenomenon in vertebrates, which is a criterion for the fundamental cause of senesc...
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Article
Evaluation of cartilage degradation in arthritis using T1ρ magnetic resonance imaging map**
T1ρ magnetic resonance imaging (MRI) can be used to map proteoglycan (PG) loss in cartilage. Here, we used T1ρ MRI to map cartilage degradation in osteoarthritis (OA) and rheumatoid arthritis (RA). Tissue samp...
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Article
Rotatory laxity evaluation of the knee using modified Slocum’s test in open magnetic resonance imaging
The authors have developed a quantitative method to evaluate rotatory laxity of the anterior cruciate ligament (ACL)-deficient knee using an open MRI. In this study, we evaluated the correlation between the pi...
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Article
Open AccessExtensive expansion and diversification of the chemokine gene family in zebrafish: Identification of a novel chemokine subfamily CX
The chemokine family plays important roles in cell migration and activation. In humans, at least 44 members are known. Based on the arrangement of the four conserved cysteine residues, chemokines are now class...