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    Article

    Structure of the mitochondrial import gate reveals distinct preprotein paths

    The translocase of the outer mitochondrial membrane (TOM) is the main entry gate for proteins14. Here we use cryo-electron microscopy to report the structure of the yeast TOM core complex59 at 3.8-Å resolution....

    Yuhei Araiso, Akihisa Tsutsumi, Jian Qiu, Kenichiro Imai, Takuya Shiota in Nature (2019)

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    Article

    1H, 13C and 15N resonance assignments for a chemokine receptor-binding domain of FROUNT, a cytoplasmic regulator of chemotaxis

    FROUNT is a cytoplasmic protein that interacts with the membrane-proximal C-terminal regions (Pro-Cs) of the CCR2 and CCR5 chemokine receptors. The interactions between FROUNT and the chemokine receptors play ...

    Sosuke Yoshinaga, Norihito Ishida, Tatsuichiro Tsuji in Biomolecular NMR Assignments (2018)

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    Article

    Identification and Preparation of a Novel Chemokine Receptor-Binding Domain in the Cytoplasmic Regulator FROUNT

    FROUNT is a cytoplasmic protein that binds to the membrane-proximal C-terminal regions (Pro-Cs) of chemokine receptors, CCR2 and CCR5. The FROUNT–chemokine receptor interactions play a pivotal role in the migr...

    Akihiro Sonoda, Sosuke Yoshinaga, Kaori Yunoki, Soichiro Ezaki in Molecular Biotechnology (2017)

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    Open Access

    Quality control of nonstop membrane proteins at the ER membrane and in the cytosol

    Since messenger RNAs without a stop codon (nonstop mRNAs) for organelle-targeted proteins and their translation products (nonstop proteins) generate clogged translocon channels as well as stalled ribosomes, ce...

    Shunsuke Arakawa, Kaori Yunoki, Toshiaki Izawa, Yasushi Tamura in Scientific Reports (2016)