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  1. Article

    Open Access

    Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis

    Takayasu arteritis (TAK) is an autoimmune large vessel vasculitis that affects the aorta and its major branches, eventually leading to the development of aortic aneurysm and vascular stenosis or occlusion. Thi...

    Yusuke Manabe, Tomohiko Ishibashi, Ryotaro Asano… in Arthritis Research & Therapy (2023)

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  2. Article

    Open Access

    Ectonucleotidase CD39 is highly expressed on ATLL cells and is responsible for their immunosuppressive function

    Adult T-cell leukemia/lymphoma (ATLL) patients have an extremely poor prognosis, partly due to their immunosuppressive state. The majority of ATLL patients have leukemic cells with phenotype similar to Tregs, ...

    Yasuhiro Nagate, Sachiko Ezoe, Jiro Fujita, Daisuke Okuzaki, Daisuke Motooka… in Leukemia (2021)

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  3. No Access

    Article

    Complementary regulation of early B-lymphoid differentiation by genetic and epigenetic mechanisms

    Although B lymphopoiesis is one of the best-defined paradigms in cell differentiation, our knowledge of the regulatory mechanisms underlying its earliest processes, in which hematopoietic stem cells (HSCs) en...

    Takafumi Yokota, Takao Sudo, Tomohiko Ishibashi… in International Journal of Hematology (2013)