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Pharmacokinetics, Safety, and Tolerability of Single-Dose Orally Administered Venglustat in Healthy Chinese Volunteers

Deficiencies of enzymes acting downstream of glucosylceramide synthase (GCS) can cause severe substrate accumulation. Venglustat is a small-molecule, brain-penetrant GCS inhibitor under investigation for multi...

Yingxin Li, Yang Li, Li Li, Wei Xue, Kong **n, Titi Wang… in Clinical Drug Investigation (2023)