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Article
Boosting the collapse performance of Wax-binder-free silica based ceramic core via adding nano-alumina sol modified fused silica powder
Wax-binder-free silica-based ceramic core with high collapsibility plays a critical role in precision casting. However, the collapse performance will dramatically reduce because the densification was induced b...
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Article
Open AccessP62 promotes FSH-induced antral follicle formation by directing degradation of ubiquitinated WT1
In females, the pathophysiological mechanism of poor ovarian response (POR) is not fully understood. Considering the expression level of p62 was significantly reduced in the granulosa cells (GCs) of POR patien...
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Article
Open AccessComparative transcriptomic analysis provides insights into the genetic networks regulating oil differential production in oil crops
Plants differ more than threefold in seed oil contents (SOCs). Soybean (Glycine max), cotton (Gossypium hirsutum), rapeseed (Brassica napus), and sesame (Sesamum indicum) are four important oil crops with markedl...
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Article
Open AccessInfluencing risk factors of voriconazole-induced liver injury in Uygur pediatric patients undergoing allogeneic hematopoietic stem cell transplantation
We aimed to investigated the influencing risk factors of voriconazole-induced liver injury in Uygur pediatric patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).
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Article
Open AccessThe association between waist circumference and adult asthma attack using nationally representative samples
This study aims to explore the relationship between waist circumference and asthma attack in adults.
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Article
Open AccessDevelopment and validation of a novel risk classification tool for predicting long length of stay in NICU blood transfusion infants
Newborns are as the primary recipients of blood transfusions. There is a possibility of an association between blood transfusion and unfavorable outcomes. Such complications not only imperil the lives of newbo...
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Article
Superhydrophobic anticorrosive fluoroethylene vinyl ether coating nanocomposited with metal-organic framework derived ferrite nanocapsules and MXene
As an enormously valuable cultural heritage, to make sure bronze relics receive more protection and extend the preservation time, the exploration and research of protective coatings for bronze are a systematic...
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Article
Allogeneic stem cell transplantation is still a highly curative therapy in adults with philadelphia chromosome–positive acute lymphoblastic leukaemia
The application of tyrosine kinase inhibitors (TKIs) and novel immunotherapies has improved outcomes in patients with Ph + acute lymphoblastic leukaemia (ALL), and the issue of whether ther...
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Article
Open AccessAIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury
The cytoplasmic pattern recognition receptor, absent in melanoma 2 (AIM2), detects cytosolic DNA, activating the inflammasome and resulting in pro-inflammatory cytokine production and pyroptotic cell death. Re...
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Article
Open AccessImmune persistence after different polio sequential immunization schedules in Chinese infants
Trivalent oral poliovirus vaccine (tOPV) has been withdrawn and instead an inactivated poliovirus vaccine (IPV) and bivalent type 1 and type 3 OPV (bOPV) sequential immunization schedule has been implemented s...
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Article
Protective Effect of Protocatechuic Acid on Oxidative Damage and Cognitive Impairment in Pb-Induced Rats
Protocatechuic acid (PCA), a class of water-soluble phenolic acid abundant in the human diet, has been shown to be of great nutritional interest and to have medicinal value. However, the protective effects aga...
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Article
Open AccessPrognostic factors for invasive mucinous adenocarcinoma of the lung: systematic review and meta-analysis
Invasive mucinous adenocarcinoma of the lung (IMA) is a unique and rare subtype of lung adenocarcinoma with poorly defined prognostic factors and highly controversial studies. Hence, this study aimed to compre...
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Article
Open AccessSingle-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions
Despite therapeutic advances, once a cancer has metastasized to the bone, it represents a highly morbid and lethal disease. One third of patients with advanced clear cell renal cell carcinoma (ccRCC) present w...
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Article
Open AccessEffects of dexmedetomidine combined with etomidate on postoperative cognitive function in older patients undergoing total intravenous anaesthesia: a randomized, double-blind, controlled trial
Etomidate has been advocated for anesthesia in older and critically ill patients because of its hemodynamic stability. Clinical studies have shown that dexmedetomidine has neuroprotective and anti-inflammatory...
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Article
Open AccessCYB561 promotes HER2+ breast cancer proliferation by inhibiting H2AFY degradation
Breast cancer (BRCA) has a high incidence and mortality rate among women. Different molecular subtypes of breast cancer have different prognoses and require personalized therapies. It is imperative to find nov...
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Article
Electronic modulation of sprout-shaped NiCoP nanoarrays by N and Ce do** for efficient overall water splitting
Bifunctional catalysts for hydrogen/oxygen evolution reactions (HER/OER) are urgently needed given the bright future of water splitting hydrogen production technology. Here, the self-supporting N and Ce dual-d...
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Article
Open AccessAssessing health state utilities for people with myalgic encephalomyelitis/chronic fatigue syndrome in Australia using the EQ-5D-5L, AQoL-8D and EQ-5D-5L-psychosocial instruments
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic condition with a constellation of symptoms presenting as severe and profound fatigue of ≥ 6 months not relieved by rest. ME/CFS affects ...
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Article
A new sensitization strategy for achieving organic RTP in aqueous solution: tunable RTP and UC emission in supramolecular TTA-UC systems
Achieving room temperature phosphorescence (RTP) of heavy-atom-free organic molecules with near-infrared (NIR) emission in solutions is fascinating for medical and biological applications but is highly challen...
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Article
Open AccessEstimating the disutility of relapse in relapsing–remitting and secondary progressive multiple sclerosis using the EQ-5D-5L, AQoL-8D, EQ-5D-5L-psychosocial, and SF-6D: implications for health economic evaluation models
Relapses are an important clinical feature of multiple sclerosis (MS) that result in temporary negative changes in quality of life (QoL), measured by health state utilities (HSUs) (disutilities). We aimed to q...
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Article
Runx1 Deficiency Promotes M2 Macrophage Polarization Through Enhancing STAT6 Phosphorylation
Our previous study had demonstrated that Runx1 promoted LPS-induced macrophage inflammatory response, however, the role of Runx1 in M2 macrophage polarization still remains largely unknown. This study was cond...
