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  1. Article

    Erratum: Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

    Nat. Biotechnol. 33, 543–548 (2015); published online 24 March 2015; corrected after print 14 December 2017 In the version of this article initially published, in the HTML only, in Online Methods “Cell culture...

    Trung Van Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst… in Nature Biotechnology (2018)

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  2. Article

    Open Access

    Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

    The CRISPR/Cas9 system is increasingly used for gene inactivation in mouse zygotes, but homology-directed mutagenesis and use of inbred embryos are less established. In particular, Rosa26 knock-in alleles for the...

    Van Trung Chu, Timm Weber, Robin Graf, Thomas Sommermann… in BMC Biotechnology (2016)

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    Article

    Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

    The efficiency of precise CRISPR/Cas9 genome editing is increased by inhibition of the nonhomologous end joining pathway.

    Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst… in Nature Biotechnology (2015)