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Article
Pediatric urogenital schistosomiasis diagnosed in France
Schistosomiasis affects approximately 230 million people worldwide. There is an increased incidence of schistosomiasis cases in France acquired from outside the country. This increases the risk of schistosomia...
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Article
Reversed cortico-medullary differentiation in the fetal and neonatal kidneys: an indicator of poor prognosis?
Bilateral reversed cortico-medullary differentiation is rarely observed on fetal or neonatal renal ultrasound and is therefore a diagnostic challenge.
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Article
Outcome of children with IgA vasculitis with nephritis treated with steroids: a matched controlled study
IgA vasculitis (IgAV) is the most common vasculitis in children. IgAV long-term prognosis depends on kidney involvement or IgA vasculitis with nephritis (IgAVN). To date, steroid treatment (oral steroids or me...
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Article
Pediatric ANCA vasculitis: clinical presentation, treatment, and outcomes in a French retrospective study
Pediatric ANCA vasculitis is a rare group of diseases with a scarcity of data in children. Annual incidence appeared to increase in the last several years, placing higher interest in the clinical and therapeu...
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Article
Predictive factors for survival in patients with oligohydramnios secondary to antenatal kidney disease
Renal oligohydramnios (ROH) is caused by bilateral congenital abnormalities, either of renal parenchymal or obstructive origin. ROH is a poor prognostic factor of neonatal survival; lung hypoplasia is reported...
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Article
Benefits of BNP/NT-proBNP serum level evaluation for dry weight adjustment in pediatric hemodialysis patients
Dry weight (DW) adjustment in children on hemodialysis (HD) can be challenging. It relies on clinical evaluation and additional supports. Our aim was to study the benefits of cardiac biomarker assessment, in a...
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Article
To biopsy or not to biopsy: Henoch-Schönlein nephritis in children, a 5-year follow-up study
The prognosis of Henoch-Schönlein purpura (HSP), IgA vasculitis, depends on kidney involvement. There is no consensus on the initiation of treatment for HSP nephritis (HSPN). Some centres start treatment befor...
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Article
Management of IgA Vasculitis with Nephritis
Immunoglobulin A (IgA) vasculitis (IgAV), previously called Henoch–Schönlein purpura, is characterized by IgA-dominant immune deposits affecting small vessels and often involves the skin, gastrointestinal trac...
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Article
Procalcitonin serum levels in stage 5 chronic kidney disease children on hemodialysis
Infections are responsible for morbidity and mortality in children on hemodialysis (HD). Procalcitonin (PCT) is rarely used in this population, even though it is an efficient biomarker of infection and sepsis....
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Article
Tolvaptan therapy to treat severe hyponatremia in pediatric nephrotic syndrome
Tolvaptan is a selective oral vasopressin V2-receptor antagonist. Some data have implicated stimulation of arginine vasopressin (AVP) as an important factor in oedema formation in a rodent model of nephrotic s...
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Article
Immunoglobulin serum levels in rituximab-treated patients with steroid-dependent nephrotic syndrome
Rituximab (RTX) is efficient in steroid-dependent nephrotic syndrome (SDNS) in pediatric and adult patients. The aim of this study is to describe hypogammaglobulinemia as a side effect of RTX treatment.
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Article
Histological prognostic factors in children with Henoch-Schönlein purpura nephritis
The management of IgA vasculitis with nephritis (IgAVN) remains controversial because of the difficulty to identify prognostic factors. This study reports the prognosis of children with IgAVN in relation to hi...
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Article
Infrequent tacrolimus-induced nephrotoxicity in French patients with steroid-dependent nephrotic syndrome
Chronic nephrotoxicity with potentially irreversible lesions is a major concern regarding calcineurin inhibitor (CNI) treatment in children with severe forms of idiopathic nephrotic syndrome (INS).
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Article
Response to “Predictors of rituximab-related neutropenia in Japanese children with steroid-dependent nephrotic syndrome”
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Article
Idiopathic nephrotic syndrome and rituximab: may we predict circulating B lymphocytes recovery?
Rituximab (RTX) has been shown to be an efficient treatment for steroid-dependent nephrotic syndrome (SDNS). A long B cell depletion period seems to improve the duration of remission. This study reports the du...
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Article
Open AccessDistinctive vasculopathy with systemic involvement due to levamisole long-term therapy: a case report
Levamisole belongs to the antihelminthic class of drugs that are sometimes administered to patients with frequently relapsing or steroid-dependent nephrotic syndrome, owing to its steroid-sparing effects. Neut...
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Article
Thrombotic microangiopathy and breastfeeding: where is the link? Answers
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Article
Thrombotic microangiopathy and breastfeeding: where is the link? Questions
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Article
Pharmacogenetics of post-transplant diabetes mellitus in children with renal transplantation treated with tacrolimus
Post-transplant diabetes mellitus (PTDM) is a major complication of immunosuppressive therapy, with many risk factors reported in adults with renal transplantation. The objective of this study was to investiga...
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Article
Clinical and genetic heterogeneity in familial steroid-sensitive nephrotic syndrome
Familial steroid-sensitive nephrotic syndrome (SSNS) is a rare condition. The disease pathophysiology remains elusive. However, bi-allelic mutations in the EMP2 gene were identified, and specific variations in HL...
