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    Article

    Pharmacogenetics of post-transplant diabetes mellitus in children with renal transplantation treated with tacrolimus

    Post-transplant diabetes mellitus (PTDM) is a major complication of immunosuppressive therapy, with many risk factors reported in adults with renal transplantation. The objective of this study was to investiga...

    Pauline Lancia, Tiphaine Adam de Beaumais, Valéry Elie… in Pediatric Nephrology (2018)

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    Article

    Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia

    The backbone of drug therapy used in acute lymphoblastic leukemia (ALL) in children includes 6-mercaptopurine (6-MP). Intracellular metabolism of this prodrug is a key component of the therapeutic response. Ma...

    Tiphaine Adam de Beaumais… in European Journal of Clinical Pharmacology (2012)