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  1. Article

    Open Access

    Fast algorithms for computing phylogenetic divergence time

    The inference of species divergence time is a key step in most phylogenetic studies. Methods have been available for the last ten years to perform the inference, but the performance of the methods does not yet...

    Ralph W. Crosby, Tiffani L. Williams in BMC Bioinformatics (2017)

  2. No Access

    Chapter and Conference Paper

    A Fast Algorithm for Computing the Quartet Distance for Large Sets of Evolutionary Trees

    We present the QuickQuartet algorithm for computing the all-to-all quartet distance for large evolutionary tree collections. By leveraging the relationship between bipartitions and quartets, our approach signi...

    Ralph W. Crosby, Tiffani L. Williams in Bioinformatics Research and Applications (2012)

  3. Article

    Open Access

    An efficient and extensible approach for compressing phylogenetic trees

    Biologists require new algorithms to efficiently compress and store their large collections of phylogenetic trees. Our previous work showed that TreeZip is a promising approach for compressing phylogenetic tre...

    Suzanne J Matthews, Tiffani L Williams in BMC Bioinformatics (2011)

  4. Article

    Open Access

    MrsRF: an efficient MapReduce algorithm for analyzing large collections of evolutionary trees

    MapReduce is a parallel framework that has been used effectively to design large-scale parallel applications for large computing clusters. In this paper, we evaluate the viability of the MapReduce framework fo...

    Suzanne J Matthews, Tiffani L Williams in BMC Bioinformatics (2010)

  5. No Access

    Chapter and Conference Paper

    Large-Scale Analysis of Phylogenetic Search Behavior

    Phylogenetic analysis is used in all branches of biology with applications ranging from studies on the origin of human populations to investigations of the transmission patterns of HIV. Most phylogenetic analy...

    Hyun Jung Park, Seung-** Sul, Tiffani L. Williams in Advances in Computational Biology (2010)

  6. No Access

    Chapter and Conference Paper

    A Novel Approach for Compressing Phylogenetic Trees

    Phylogenetic trees are tree structures that depict relationships between organisms. Popular analysis techniques often produce large collections of candidate trees, which are expensive to store. We introduce Tr...

    Suzanne J. Matthews, Seung-** Sul in Bioinformatics Research and Applications (2010)

  7. Article

    Open Access

    Using tree diversity to compare phylogenetic heuristics

    Evolutionary trees are family trees that represent the relationships between a group of organisms. Phylogenetic heuristics are used to search stochastically for the best-scoring trees in tree space. Given that...

    Seung-** Sul, Suzanne Matthews, Tiffani L Williams in BMC Bioinformatics (2009)

  8. No Access

    Chapter and Conference Paper

    An Experimental Analysis of Consensus Tree Algorithms for Large-Scale Tree Collections

    Consensus trees are a popular approach for summarizing the shared evolutionary relationships in a collection of trees. Many popular techniques such as Bayesian analyses produce results that can contain tens of...

    Seung-** Sul, Tiffani L. Williams in Bioinformatics Research and Applications (2009)

  9. No Access

    Chapter and Conference Paper

    A Fitness Distance Correlation Measure for Evolutionary Trees

    Phylogenetics is concerned with inferring the genealogical relationships between a group of organisms (or taxa), and this relationship is usually expressed as an evolutionary tree. However, inferring the phylo...

    Hyun Jung Park, Tiffani L. Williams in Bioinformatics and Computational Biology (2009)

  10. No Access

    Chapter and Conference Paper

    Efficiently Computing Arbitrarily-Sized Robinson-Foulds Distance Matrices

    In this paper, we introduce the HashRF(p,q) algorithm for computing RF matrices of large binary, evolutionary tree collections. The novelty of our algorithm is that it can be used to compute arbitrarily-sized (p ...

    Seung-** Sul, Grant Brammer, Tiffani L. Williams in Algorithms in Bioinformatics (2008)

  11. No Access

    Chapter and Conference Paper

    An Experimental Analysis of Robinson-Foulds Distance Matrix Algorithms

    In this paper, we study two fast algorithms—HashRF and PGM-Hashed—for computing the Robinson-Foulds (RF) distance matrix between a collection of evolutionary trees. The RF distance matrix represents a tremendo...

    Seung-** Sul, Tiffani L. Williams in Algorithms - ESA 2008 (2008)

  12. No Access

    Chapter

    Performance of Supertree Methods on Various Data Set Decompositions

    Many large-scale phylogenetic reconstruction methods attempt to solve hard optimization problems such as Maximum Parsimony (MP) and Maximum Likelihood (ML), but they are severely limited by the number of taxa ...

    Usman Roshan, Bernard M. E. Moret, Tiffani L. Williams in Phylogenetic Supertrees (2004)

  13. No Access

    Chapter and Conference Paper

    The Heterogeneous Bulk Synchronous Parallel Model

    Trends in parallel computing indicate that heterogeneous parallel computing will be one of the most widespread platforms for computation-intensive applications. A heterogeneous computing environment offers con...

    Tiffani L. Williams, Rebecca J. Parsons in Parallel and Distributed Processing (2000)