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  1. Article

    Open Access

    Partial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2

    Isabella Randerath, Natalia Quinete, Julian Peter Müller in Archives of Toxicology (2024)

  2. Article

    Open Access

    Ten years after: findings from the medical surveillance program on Health Effects in High-Level Exposure to PCB (HELPcB)

    After the detection of high environmental and occupational exposure to polychlorinated biphenyls (PCBs) in a German recycling company for transformers and capacitors in 2010, the multidisciplinary medical surv...

    Jens Rengelshausen, Isabella Randerath, Thomas Schettgen in Archives of Toxicology (2023)

  3. Article

    Open Access

    Longitudinal changes in telomere length in PCB-exposed individuals: interaction with CMV infection

    We recently demonstrated a significant shortening of age-adapted telomere length (TL) in lymphocytes of polychlorinated biphenyls (PCB)-exposed individuals. Here, we analyzed TL in individuals of the same PCB-...

    Fabian Beier, Andre Esser, Lucia Vankann, Anne Abels in Archives of Toxicology (2021)

  4. No Access

    Reference Work Entry In depth

    Medical Aspects of Traffic Exhaust Regulations

    Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...

    Andrea Kaifie, Thomas Kraus in Regulatory Toxicology (2021)

  5. No Access

    Living Reference Work Entry In depth

    Medical Aspects of Traffic Exhaust Regulations

    Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...

    Andrea Kaifie, Thomas Kraus in Regulatory Toxicology

  6. Article

    Open Access

    Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure

    Polychlorinated biphenyls (PCBs) are organochlorine pollutants with a worldwide dissemination. We examined telomere length (TL) in peripheral blood cells of 207 individuals with a high body burden of PCBs due ...

    Susanne Ziegler, Thomas Schettgen, Fabian Beier, Stefan Wilop in Archives of Toxicology (2017)

  7. No Access

    Article

    Characterization of the sigma ligand panamesine, a potential antipsychotic, by immune response in patients with schizophrenia and by sleep-EEG changes in normal controls

    Panamesine (PAN) is a nearly specific sigma ligand. Recently, we showed that PAN in doses up to 90 mg/day improved psychometric variables in patients with an acute episode of schizophrenia. No side effects co...

    R.-M. Frieboes, Harald Murck, Irina Antonijevic, Thomas Kraus in Psychopharmacology (1999)