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    Article

    Efficient gene transfer into lymphoma cells using adenoviral vectors combined with lipofection

    Tumor cells, such as lymphoma cells, are possible targets for gene therapy. In general, gene therapeutic approaches require efficient gene transfer to host cells and sufficient transgene expression. However, l...

    Peter Buttgereit, Silvia Weineck, Gabriele Röpke, Angela Märten… in Cancer Gene Therapy (2000)

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    Article

    Retroviral gene transfer of dominant negative Raf-1 mutants suppresses Ha-ras-induced transformation and delays tumor formation

    Activating mutants of ras are among the most frequently found genetic alterations in human cancers. Therefore, Ras appears to be an attractive target for therapeutic intervention using gene transfer. The protein ...

    Thomas Heinicke, Gerald Radziwill, Michael Nawrath, Christian Rommel… in Cancer Gene Therapy (2000)