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    Article

    Increase in proliferation rate and normalization of TNF-α secretion by blockage of gene transfer–induced apoptosis in lymphocytes using low-dose cyclosporine A

    Efficient gene transfer of lymphocytes is extremely difficult. We have shown previously that induction of apoptosis may play a role in the gene transfer resistance of lymphocytes. Anti-CD3 antibody can be used...

    Gabriele Röpke, Oliver Ebert, Angela Märten, Petja Lefterova… in Cancer Gene Therapy (2000)

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    Article

    Efficient gene transfer into lymphoma cells using adenoviral vectors combined with lipofection

    Tumor cells, such as lymphoma cells, are possible targets for gene therapy. In general, gene therapeutic approaches require efficient gene transfer to host cells and sufficient transgene expression. However, l...

    Peter Buttgereit, Silvia Weineck, Gabriele Röpke, Angela Märten… in Cancer Gene Therapy (2000)