6 Result(s)
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Terence S. Dermody
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessStructure of orthoreovirus RNA chaperone σNS, a component of viral replication factories
The mammalian orthoreovirus (reovirus) σNS protein is required for formation of replication compartments that support viral genome replication and capsid assembly. Despite its functional importance, a mechanis...
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Article
Open AccessPaired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus
Mammalian orthoreovirus (reovirus) infects most mammals and is associated with celiac disease in humans. In mice, reovirus infects the intestine and disseminates systemically to cause serotype-specific pattern...
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Article
Open AccessAuthor Correction: Reovirus directly engages integrin to recruit clathrin for entry into host cells
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Article
Open AccessReovirus directly engages integrin to recruit clathrin for entry into host cells
Reovirus infection requires the concerted action of viral and host factors to promote cell entry. After interaction of reovirus attachment protein σ1 with cell-surface carbohydrates and proteinaceous receptors...
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Article
Open AccessGlycan-mediated enhancement of reovirus receptor binding
Viral infection is an intricate process that requires the concerted action of both viral and host cell components. Entry of viruses into cells is initiated by interactions between viral proteins and their cell...
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Article
Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
The innate immune receptor RIG-I is shown to sense 5′-diphosphate RNAs as found in some viral genomes in addition to its well characterized activation by RNAs bearing 5′-triphosphate moieties.
