17 Result(s)

Article

Changes in choroidal thickness in healthy participants after induction of sympathetic hyperactivity using the cold pressor test

Rino Umemoto, Yuki Hashimoto… in Graefe's Archive for Clinical and Experime… (2023)

Article

Peripapillary choroidal thickness assessed by spectral-domain optical coherence tomography in normal Japanese

To investigate peripapillary choroidal thickness (PPCT) in normal Japanese subjects by using spectral-domain optical coherence tomography (SD-OCT) with enhanced depth imaging (EDI) technique and evaluate its a...

Hitomi Shibata, Yu Sawada, Makoto Ishikawa… in Japanese Journal of Ophthalmology (2021)

Article

Long-term regular exercise and intraocular pressure: the Hisayama Study

To investigate the association between long-term regular exercise (exercise frequency and exercise time) and 5-year changes in intraocular pressure in a general Japanese population.

Kohta Fujiwara, Miho Yasuda, Jun Hata… in Graefe's Archive for Clinical and Experime… (2019)

Article

Effects of ripasudil hydrochloride hydrate (K-115), a Rho-kinase inhibitor, on ocular blood flow and ciliary artery smooth muscle contraction in rabbits

Ripasudil, a Rho-associated coiled-coil-containing protein kinase (ROCK) inhibitor, is a novel drug for glaucoma in Japan. ROCK inhibition not only reduces intraocular pressure (IOP) but also increases ocular ...

Yusuke Ohta, Sanae Takaseki, Takeshi Yoshitomi in Japanese Journal of Ophthalmology (2017)

Article

Dorzolamide-induced relaxation of isolated rabbit ciliary arteries mediated by inhibition of extracellular calcium influx

The carbonic anhydrase inhibitor dorzolamide can increase optic nerve blood flow. The aim of the study reported here was to investigate the effect of dorzolamide on isolated rabbit ciliary arteries that supply...

Yaru Dong, Yu Sawada, Jizhe Cui, Masahiro Hayakawa… in Japanese Journal of Ophthalmology (2016)

Article

Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries

In normotensive eyes, reduced ocular blood flow can lead to glaucoma pathogenesis. Drugs that reduce intraocular pressure (IOP) often cause vasodilation of the ciliary arteries and improve blood flow to the ey...

Hiroshi Watabe, Sanae Abe, Takeshi Yoshitomi in Japanese Journal of Ophthalmology (2011)

Article

Spontaneous closure of a stage 2 macular hole without detachment of the posterior hyaloid

Sanae Abe, Toshiyuki Fujiwara, Takeshi Yoshitomi in Japanese Journal of Ophthalmology (2010)

Article

Temperature-dependent ultrastructural changes in the cone interphotoreceptor matrix

To determine the temperature-dependent ultrastructural changes of the cone matrix sheath, a possible critical factor in the adhesive strength binding photoreceptors and pigment epithelial cells.

Makoto Ishikawa, Toshiyuki Fujiwara, Takeshi Yoshitomi in Japanese Journal of Ophthalmology (2009)

Article

Effect and Mechanism of Betaxolol and Timolol on Vascular Relaxation in Isolated Rabbit Ciliary Artery

In order to clarify the vasodilatory mechanism of betaxolol and timolol, we studied the effects of these drugs in isolated rabbit ciliary arteries.

Yaru Dong, Hitoshi Ishikawa, Yazhen Wu, Kimiya Shimizu… in Japanese Journal of Ophthalmology (2006)

Article

Effect of Immunosuppression on Survival of Allograft Limbal Stem Cells

To examine whether the application of immunosuppression enhances the survival of limbal allograft stem cells.

Wensheng Chen, Lihui Cao, Koji Hara, Takeshi Yoshitomi in Japanese Journal of Ophthalmology (2004)

Article

Multiple retinal holes in the macular region: a case report

Purpose. To describe the first case of multiple retinal holes in the macular region successfully treated with vitrectomy.

Shizuya Saika, Yuko Hayashi… in Graefe's Archive for Clinical and Experime… (2002)

Article

Pharmacological effects of latanoprost, prostaglandin E₂, and F_{2 α} on isolated rabbit ciliary artery

Background: Latanoprost is a prostaglandin (PG)F_{2 α} analogue widely recognized in the treatment of glaucoma. To investigate the action of this drug on the ocular ...

Hitoshi Ishikawa, Takeshi Yoshitomi… in Graefe's Archive for Clinical and Experime… (2002)

Article

Effect of histamine and substance P on the rabbit and human iris sphincter muscle

• Background and methods: In an attempt to clarify the functional action of histamine and substance P on atropine-resistant miosis, we isolated rabbit and human iris sphincter muscles and investigated their me...

Takeshi Yoshitomi, Hitoshi Ishikawa… in Graefe's Archive for Clinical and Experime… (1995)

Article

Functional innervation of bovine ophthalmic artery

To investigate the functional innervation pattern in smooth muscle of bovine ophthalmic artery, we studied the effect of electrical stimulation and various drugs on the mechanical responses of this muscle usin...

Takeshi Yoshitomi… in Graefe's Archive for Clinical and Experimental Ophthalmology (1994)

Article

Granular cell tumor of the lower lid: histological and immunohistochemical studies

Histological and immunohistochemical studies of a granular cell tumor involving the lower lid are described. Histological examination showed it to have typical features of a granular cell tumor. Nervous-system...

Tatsuro Ishibashi, Takeshi Yoshitomi… in Graefe's Archive for Clinical and Experime… (1984)