-
Article
Open AccessFactors associated with visual field or structure progression occurring first in a prospective study on patients with untreated open-angle glaucoma with normal intraocular pressure
To identify factors associated with disc/retina deterioration in stereo fundus photographs preceding that of the visual field (VF), as determined with a Humphrey Field Analyzer (HFA) (Structure First deteriora...
-
Article
Changes in choroidal thickness in healthy participants after induction of sympathetic hyperactivity using the cold pressor test
-
Article
Peripapillary choroidal thickness assessed by spectral-domain optical coherence tomography in normal Japanese
To investigate peripapillary choroidal thickness (PPCT) in normal Japanese subjects by using spectral-domain optical coherence tomography (SD-OCT) with enhanced depth imaging (EDI) technique and evaluate its a...
-
Article
Long-term regular exercise and intraocular pressure: the Hisayama Study
To investigate the association between long-term regular exercise (exercise frequency and exercise time) and 5-year changes in intraocular pressure in a general Japanese population.
-
Article
Effects of ripasudil hydrochloride hydrate (K-115), a Rho-kinase inhibitor, on ocular blood flow and ciliary artery smooth muscle contraction in rabbits
Ripasudil, a Rho-associated coiled-coil-containing protein kinase (ROCK) inhibitor, is a novel drug for glaucoma in Japan. ROCK inhibition not only reduces intraocular pressure (IOP) but also increases ocular ...
-
Article
Dorzolamide-induced relaxation of isolated rabbit ciliary arteries mediated by inhibition of extracellular calcium influx
The carbonic anhydrase inhibitor dorzolamide can increase optic nerve blood flow. The aim of the study reported here was to investigate the effect of dorzolamide on isolated rabbit ciliary arteries that supply...
-
Article
Open AccessMorning glory disc anomaly with contractile movements
-
Article
Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries
In normotensive eyes, reduced ocular blood flow can lead to glaucoma pathogenesis. Drugs that reduce intraocular pressure (IOP) often cause vasodilation of the ciliary arteries and improve blood flow to the ey...
-
Article
Spontaneous closure of a stage 2 macular hole without detachment of the posterior hyaloid
-
Article
Temperature-dependent ultrastructural changes in the cone interphotoreceptor matrix
To determine the temperature-dependent ultrastructural changes of the cone matrix sheath, a possible critical factor in the adhesive strength binding photoreceptors and pigment epithelial cells.
-
Article
Effect and Mechanism of Betaxolol and Timolol on Vascular Relaxation in Isolated Rabbit Ciliary Artery
In order to clarify the vasodilatory mechanism of betaxolol and timolol, we studied the effects of these drugs in isolated rabbit ciliary arteries.
-
Article
Effect of Immunosuppression on Survival of Allograft Limbal Stem Cells
To examine whether the application of immunosuppression enhances the survival of limbal allograft stem cells.
-
Article
Multiple retinal holes in the macular region: a case report
Purpose. To describe the first case of multiple retinal holes in the macular region successfully treated with vitrectomy.
-
Article
Pharmacological effects of latanoprost, prostaglandin E2, and F2 α on isolated rabbit ciliary artery
Background: Latanoprost is a prostaglandin (PG)F2 α analogue widely recognized in the treatment of glaucoma. To investigate the action of this drug on the ocular ...
-
Article
Effect of histamine and substance P on the rabbit and human iris sphincter muscle
• Background and methods: In an attempt to clarify the functional action of histamine and substance P on atropine-resistant miosis, we isolated rabbit and human iris sphincter muscles and investigated their me...
-
Article
Functional innervation of bovine ophthalmic artery
To investigate the functional innervation pattern in smooth muscle of bovine ophthalmic artery, we studied the effect of electrical stimulation and various drugs on the mechanical responses of this muscle usin...
-
Article
Granular cell tumor of the lower lid: histological and immunohistochemical studies
Histological and immunohistochemical studies of a granular cell tumor involving the lower lid are described. Histological examination showed it to have typical features of a granular cell tumor. Nervous-system...