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  1. Article

    Open Access

    Artificial intelligence for volumetric measurement of cerebral white matter hyperintensities on thick-slice fluid-attenuated inversion recovery (FLAIR) magnetic resonance images from multiple centers

    We aimed to develop a new artificial intelligence software that can automatically extract and measure the volume of white matter hyperintensities (WMHs) in head magnetic resonance imaging (MRI) using only thic...

    Masashi Kuwabara, Fusao Ikawa, Shinji Nakazawa, Saori Koshino in Scientific Reports (2024)

  2. Article

    Open Access

    Animal-borne soundscape logger as a system for edge classification of sound sources and data transmission for monitoring near-real-time underwater soundscape

    The underwater environment is filled with various sounds, with its soundscape composed of biological, geographical, and anthropological sounds. Our work focused on develo** a novel method to observe and clas...

    Takuji Noda, Takuya Koizumi, Naoto Yukitake, Daisuke Yamamoto in Scientific Reports (2024)

  3. No Access

    Article

    Development of artificial intelligence-based slow-motion echocardiography and clinical usefulness for evaluating regional wall motion abnormalities

    The diagnostic accuracy of exercise stress echocardiography (ESE) for myocardial ischemia requires improvement, given that it currently depends on the physicians’ experience and image quality. To address this ...

    Yuki Sahashi, Ryo Takeshita in The International Journal of Cardiovascula… (2024)

  4. Article

    Correction to: Additive effects of brimonidine tartrate 0.1%/brinzolamide 1% fixed‑dose combination in prostaglandin analog‑treated Japanese glaucoma patients

    Rei Sakata, Shiro Mizoue, Keiji Yoshikawa in Japanese Journal of Ophthalmology (2024)

  5. No Access

    Chapter

    Diagnosis and Management of Tethered Cord Syndrome

    Tethered cord syndrome is a condition in which the spinal cord is tethered by pathological structures such as a tight filum terminale, intradural lipomas with or without a connecting extradural component, intr...

    Takeshi Hara, Yukoh Ohara in Advances and Technical Standards in Neurosurgery (2024)

  6. Article

    Open Access

    Comparison of the prognostic impact of IPI and PIT in peripheral T-cell lymphoma in real-world practice with a large elderly population

    We compared the predictive ability of the International Prognostic Index (IPI), a frequently used prognostic model for peripheral T-cell lymphoma (PTCL), with that of a type-specific prognostic model, the Prog...

    Nobuhiko Nakamura, Nobuhiro Kanemura, Takuro Matsumoto in Scientific Reports (2023)

  7. No Access

    Article

    Additive effects of brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination in prostaglandin analog-treated Japanese glaucoma patients

    A brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination (BBFC) was recently approved for glaucoma and ocular hypertension treatment in Japan. We investigated the efficacy and safety of BBFC used con...

    Rei Sakata, Shiro Mizoue, Keiji Yoshikawa in Japanese Journal of Ophthalmology (2023)

  8. No Access

    Article

    Flow volume mismatch dramatically affects transient neurologic symptoms after direct bypass in Moyamoya disease

    Transient neurological events (TNEs) occur after bypass surgery in Moyamoya disease (MMD); however, their pathology remains unknown. To elucidate the pathophysiology of TNEs, we investigated their relationship...

    Yuyo Maeda, Takahito Okazaki, Shinji Kume, Reo Kawano in Neurosurgical Review (2023)

  9. Article

    Open Access

    Effectiveness of deep learning classifiers in histopathological diagnosis of oral squamous cell carcinoma by pathologists

    The study aims to identify histological classifiers from histopathological images of oral squamous cell carcinoma using convolutional neural network (CNN) deep learning models and shows how the results can imp...

    Shintaro Sukegawa, Sawako Ono, Futa Tanaka, Yuta Inoue, Takeshi Hara in Scientific Reports (2023)

  10. Article

    Open Access

    Prognostic value of metabolic tumor volume of extranodal involvement in diffuse large B cell lymphoma

    Extranodal involvement predicts poor outcomes of diffuse large B cell lymphoma (DLBCL), but the impact of the metabolic tumor burden (MTV) of extranodal sites using positron emission tomography has not been cl...

    Kana Oiwa, Kei Fujita, Shin Lee, Tetsuji Morishita in Annals of Hematology (2023)

  11. Article

    Open Access

    Survey on electronic visual field data transfer practices among Japan Glaucoma Society board members

    Visual field (VF) testing in combination with a specialized VF analysis software is critical for characterizing and monitoring visual loss in glaucoma. Although performing glaucoma progression analysis require...

    Masaki Tanito, Takeshi Hara, Makoto Aihara in BMC Ophthalmology (2023)

  12. No Access

    Article

    The impact of high-resolution cone-beam CT findings on decision-making for the treatment of unruptured middle cerebral artery aneurysms

    Even with the advent of endovascular treatment for intracranial aneurysms, microsurgical clip** continues to play a significant role in the treatment of middle cerebral artery (MCA) aneurysms. Securing perfo...

    Toshinori Matsushige, Yukishige Hashimoto, Taichi Ogawa in Neurosurgical Review (2022)

  13. Article

    Open Access

    Deep learning model for analyzing the relationship between mandibular third molar and inferior alveolar nerve in panoramic radiography

    In this study, the accuracy of the positional relationship of the contact between the inferior alveolar canal and mandibular third molar was evaluated using deep learning. In contact analysis, we investigated ...

    Shintaro Sukegawa, Futa Tanaka, Takeshi Hara, Kazumasa Yoshii in Scientific Reports (2022)

  14. Article

    Open Access

    Three-dimensional morphological analysis of the thoracic pedicle and related radiographic factors in adolescent idiopathic scoliosis

    This study aimed to investigate the laterality of the pedicle morphology at the apical vertebra (AV) level and identify the radiographic factors associated with the laterality ratio of the pedicle morphology a...

    Tatsuya Sato, Hidetoshi Nojiri, Takatoshi Okuda in BMC Musculoskeletal Disorders (2022)

  15. Article

    Open Access

    Effective deep learning for oral exfoliative cytology classification

    The use of sharpness aware minimization (SAM) as an optimizer that achieves high performance for convolutional neural networks (CNNs) is attracting attention in various fields of deep learning. We used deep le...

    Shintaro Sukegawa, Futa Tanaka, Keisuke Nakano, Takeshi Hara in Scientific Reports (2022)

  16. Article

    Open Access

    Trajectory to local extinction of an isolated dugong population near Okinawa Island, Japan

    A small animal population becomes extinct owing to demographic and environmental stochasticity after declining below the minimum viable population (MVP). However, the actual process of extinction derived by st...

    Hajime Kayanne, Takeshi Hara, Nobuaki Arai, Hiroya Yamano in Scientific Reports (2022)

  17. Article

    Open Access

    A multicenter phase II study of bendamustine, rituximab, and cytarabine (BRAC) for relapsed or refractory patients with follicular lymphoma or mantle cell lymphoma

    This phase II clinical trial aimed to evaluate the efficacy and safety of the combination therapy of bendamustine, cytarabine, and rituximab (BRAC) in patients with relapsed or refractory follicular lymphoma (...

    Nobuhiko Nakamura, Senji Kasahara, Junichi Kitagawa in Experimental Hematology & Oncology (2022)

  18. Article

    Open Access

    Evaluation of multi-task learning in deep learning-based positioning classification of mandibular third molars

    Pell and Gregory, and Winter’s classifications are frequently implemented to classify the mandibular third molars and are crucial for safe tooth extraction. This study aimed to evaluate the classification accu...

    Shintaro Sukegawa, Tamamo Matsuyama, Futa Tanaka, Takeshi Hara in Scientific Reports (2022)

  19. No Access

    Chapter

    Function Integrated Diagnostic Assistance Based on MCA Models

    This article describes the summary of our research achievement on the function integrated diagnostic assistance based on multidisciplinary computational anatomy (MCA) models. The main purpose of our research w...

    Hiroshi Fujita, Takeshi Hara, **angrong Zhou in Multidisciplinary Computational Anatomy (2022)

  20. Article

    IJCARS–JAMIT 2019–2020 special issue

    Shouhei Hanaoka, Takeshi Hara in International Journal of Computer Assisted… (2021)

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