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  1. Article

    Open Access

    Squamous cell carcinoma initially occurring on the tongue dorsum: a case series report with molecular analysis

    Squamous cell carcinoma (SCC) of the dorsum of the tongue is extremely rare, and it clinically resembles various benign lesions. Somatic mutations in TP53 and some driver genes were implicated in the development ...

    Sawako Ono, Katsutoshi Hirose, Shintaro Sukegawa, Kyoichi Obata in Diagnostic Pathology (2024)

  2. Article

    Open Access

    Clear Cell Squamous Cell Carcinoma of the Maxillary Gingiva Associated with PIK3CA and HRAS Mutations: Report of a Case and Literature Review

    Squamous cell carcinoma (SCC) is the most common oral malignancy, and somatic mutations in some driver genes have been implicated in SCC development. Clear cell SCC (CCSCC) is a rare histological variant of SC...

    Katsutoshi Hirose, Takumi Shibahara, Akari Teramoto, Yu Usami in Head and Neck Pathology (2023)

  3. Article

    Open Access

    Effectiveness of deep learning classifiers in histopathological diagnosis of oral squamous cell carcinoma by pathologists

    The study aims to identify histological classifiers from histopathological images of oral squamous cell carcinoma using convolutional neural network (CNN) deep learning models and shows how the results can imp...

    Shintaro Sukegawa, Sawako Ono, Futa Tanaka, Yuta Inoue, Takeshi Hara in Scientific Reports (2023)

  4. Article

    Open Access

    Multiple orthokeratinized odontogenic cysts: clinical, pathological, and genetic characteristics

    Orthokeratinized odontogenic cyst (OOC) is a rare developmental odontogenic cyst of the jaw. It was originally believed to be a variant of odontogenic keratocyst (OKC) but is now considered to be a distinct en...

    Sawako Ono, Katsutoshi Hirose, Shintaro Sukegawa, Satoko Nakamura in Diagnostic Pathology (2022)

  5. Article

    Open Access

    Effective deep learning for oral exfoliative cytology classification

    The use of sharpness aware minimization (SAM) as an optimizer that achieves high performance for convolutional neural networks (CNNs) is attracting attention in various fields of deep learning. We used deep le...

    Shintaro Sukegawa, Futa Tanaka, Keisuke Nakano, Takeshi Hara in Scientific Reports (2022)

  6. Article

    Open Access

    Clinical study on primary screening of oral cancer and precancerous lesions by oral cytology

    This study was conducted to compare the histological diagnostic accuracy of conventional oral-based cytology and liquid-based cytology (LBC) methods.

    Shintaro Sukegawa, Sawako Ono, Keisuke Nakano, Kiyofumi Takabatake in Diagnostic Pathology (2020)

  7. Article

    Open Access

    Invasive non-typeable Haemophilus influenzae infection due to endometritis associated with adenomyosis

    The widespread administration of the Haemophilus influenzae type b vaccine has led to the predominance of non-typable H. influenzae (NTHi). However, the occurrence of invasive NTHi infection based on gynecologic ...

    Yoshito Nishimura, Hideharu Hagiya, Kaoru Kawano, Yuya Yokota in BMC Infectious Diseases (2020)