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  1. No Access

    Article

    Trace Elements in Tissues of Whale Sharks (Rhincodon typus) Stranded in the Gulf of California, Mexico

    Concentration of essential (Se, Zn and Cu) and non-essential (As, Cd, Hg and Pb) trace elements were measured in selected tissues of two dead whale sharks (Rhincodon typus) stranded in the Gulf of California (GC)...

    F. Pancaldi, F. Páez-Osuna… in Bulletin of Environmental Contamination an… (2019)

  2. No Access

    Article

    Global Distribution of Halogenated Dimethyl Bipyrroles in Marine Mammal Blubber

    Four halogenated dimethyl bipyrroles (HDBPs), hypothesized to be naturally produced, were quantitated in marine mammal blubber from a number of species obtained from various locations worldwide. HDBPs were fou...

    S. Tittlemier, A. Borrell, J. Duffe… in Archives of Environmental Contamination an… (2002)

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    Article

    In Vivo–In Vitro Correlation (IVIVC) Modeling Incorporating a Convolution Step

    The purpose of in vivo–in vitro correlation (IVIVC) modeling is described. These models are usually fitted to deconvoluted data rather than the raw plasma drug concentration/time data. Such a two-stage analysi...

    T. O'Hara, S. Hayes, J. Davis, J. Devane… in Journal of Pharmacokinetics and Pharmacody… (2001)

  4. No Access

    Chapter

    Determination of Critical Manufacturing and Formulation Variables for a Hydrophilic Matrix Tablet Formulation Using an in Vitro Discriminatory Dissolution Method

    Formulation and manufacturing variables have been reported to influence the in-vitro release from hydrophilic matrix formulations. Studies on formulation and manufacturing variables have examined drug concentrati...

    P. Stark, A. Kinahan, S. Cunningham, J. Butler, T. O’Hara… in In Vitro-in Vivo Correlations (1997)