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Open AccessA human immunodeficiency syndrome caused by mutations in CARMIL2
Human T-cell function is dependent on T-cell antigen receptor (TCR) and co-signalling as evidenced by immunodeficiencies affecting TCR-dependent signalling pathways. Here, we show four human patients with EBV+ di...
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Article
MiRNome and transcriptome aided pathway analysis in human regulatory T cells
Owing to their manifold immune regulatory functions, regulatory T cells (Treg) have received tremendous interest as targets for therapeutic intervention of diverse immunological pathologies or cancer. Directed...