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within T. Kohama Remove this filter Cancer Research Remove this filter

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  1. No Access

    Article

    Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

    We examined the involvement of sphingosine kinase-1 (SphK1), which governs the ceramide/sphingosine-1-phosphate balance, in susceptibility to imatinib of either sensitive or resistant chronic myeloid leukemia ...

    E Bonhoure, A Lauret, D J Barnes, C Martin, B Malavaud, T Kohama, J V Melo… in Leukemia (2008)

  2. No Access

    Article

    Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting shingosine kinase-1

    We examined the involvement of sphingosine kinase-1, a critical regulator of the sphingolipid balance, in susceptibility to antineoplastic agents of either sensitive or multidrug-resistant acute myeloid leukem...

    E Bonhoure, D Pchejetski, N Aouali, H Morjani, T Levade, T Kohama, O Cuvillier in Leukemia (2006)