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  1. No Access

    Article

    Microalbuminuria in Rats Treated with D-Nitroarginine Methyl Ether

    Microalbuminuria is an early symptom and prognostic marker of the progression of renal pathology. The analysis of the role of anionic components of the renal glomeruli in the albumin retention and the developm...

    E. V. Balbotkina, T. A. Karavashkina… in Bulletin of Experimental Biology and Medic… (2024)

  2. No Access

    Article

    Effect of Neurohypophysial Hormones on Protein Excretion by the Kidneys

    Vasopressin (VP) is one of the main factors affecting intraglomerular hemodynamics, filtration pressure, and the state of mesangial cells contributing to proteinuria progression. The aim of this work was to st...

    T. A. Karavashkina, E. V. Balbotkina… in Journal of Evolutionary Biochemistry and P… (2023)

  3. No Access

    Article

    Role of Proglucagon Peptides in Osmoregulation

    Glucagon-like peptide-1 (GLP-1), a product of partial proteolysis of proglucagon, is involved not only in regulation of carbohydrates, but also in water-salt metabolism. The study examined the role of progluca...

    T. A. Karavashkina, E. V. Balbotkina… in Bulletin of Experimental Biology and Medic… (2021)

  4. No Access

    Article

    Effect of the Glucagon-like Peptide-1 Mimetic on Ion- and Osmoregulating Renal Functions in Normoglycemia and Hyperglycemia

    Incretins are hormones with a wide range of biological activity. We studied the ratio of the glycemic effect of the glucagon-like peptide-1 mimetic and its effect on the renal excretion of sodium and water. It...

    A. V. Kutina, E. V. Balbotkina, T. A. Karavashkina, E. I. Shakhmatova in Human Physiology (2019)

  5. No Access

    Article

    The mechanism of glucagon-like peptide-1 participation in the osmotic homeostasis

    We have found the physiological mechanism of intensification of the excessive fluid removal from the body under the action of glucagon-like peptide-1 and its analog exenatide. Under the water load in rats, exe...

    Yu. V. Natochin, A. S. Marina, A. V. Kutina… in Doklady Biological Sciences (2016)

  6. No Access

    Article

    Effects of Selective Agonists of V1a, V2, and V1b Receptors on Sodium Transport in Rat Kidney

    The role of subtypes of vasopressin receptors in modulation of renal sodium reabsorption was studied in in vivo experiments on Wistar rats. Selective V1a receptor agonist reduced sodium reabsorption in the kidney...

    D. V. Golosova, T. A. Karavashkina… in Bulletin of Experimental Biology and Medic… (2016)

  7. No Access

    Article

    The effects of neurohypophysial nonapeptides and their analogs on magnesium excretion in rat kidney

    The effects of vertebrate neurohypophysial nonapeptides (vasopressin, vasotocin and their synthesized analogs) on urinary magnesium excretion were studied in rats. Neurohypophysial hormones and their analogs a...

    A. V. Kutina, T. A. Karavashkina… in Journal of Evolutionary Biochemistry and P… (2014)

  8. No Access

    Article

    Correlation of renal solute-free water reabsorption and energy of interaction of vasotocin analogs with V2 receptor

    The nonapeptide-receptor interaction energy calculated from docking algorithms was compared with the effect of the same peptides upon solute-free water reabsorption in rat kidney in vivo. Vasotocin and some of...

    A. V. Kutina, T. A. Karavashkina, E. I. Shakhmatova, J. Gao… in Biology Bulletin (2011)