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Article
Buccal absorption of enalapril and lisinopril
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Article
A pharmacokinetic and pharmacodynamic evaluation of buffered sublingual captopril in patients with congestive heart failure
Objective: The pharmacokinetics and pharmacodynamics of buffered sublingual captopril were assessed in patients with congestive heart failure (CHF).
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Article
The effect of pH on the buccal and sublingual absorption of captopril
The effect of pH on the buccal and sublingual absorption of captopril was evaluated using in vitro techniques and human studies. Partitioning of captopril into n-octanol was lowest over the pH range 5 to 8 and...
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Article
Sublingual captopril — a pharmacokinetic and pharmacodynamic evaluation
In this study we compared the pharmacokinetics and pharmacodynamics of captopril after sublingual and peroral administration. Single 25 mg doses of captopril were administered sublingually and perorally on two...