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    Article

    The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures

    Expression of the AF4–MLL fusion protein in murine hematopoietic progenitor/stem cells results in the development of proB acute lymphoblastic leukemia. In this study, we affinity purified the AF4–MLL and AF4 p...

    A Benedikt, S Baltruschat, B Scholz, A Bursen, T N Arrey, B Meyer, L Varagnolo in Leukemia (2011)