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Article
Open AccessSchizophrenia copy number variants and associative learning
Large-scale genomic studies have made major progress in identifying genetic risk variants for schizophrenia. A key finding from these studies is that there is an increased burden of genomic copy number variant...
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Article
Open AccessInhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL
The ALOX5 gene encodes 5-lipoxygenase (5-LO), a key enzyme of inflammatory reactions, which is transcriptionally activated by trichostatin A (TSA). Physiologically, 5-LO expression is induced by calcitriol and/or...
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Article
The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures
Expression of the AF4–MLL fusion protein in murine hematopoietic progenitor/stem cells results in the development of proB acute lymphoblastic leukemia. In this study, we affinity purified the AF4–MLL and AF4 p...
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Chapter and Conference Paper
Eine Mutation innerhalb der ATP8-Synthase verbessert den hepatischen Energiestatus im murinen Modell des akuten septischen Leberversagens
The (dys)function of mitochondria plays an important role in the development of multiple organ failure. Therefore, the implications of mitochondrial (dys)function in the development of multiple organ failure a...
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Article
Open AccessT Cell transformation by herpesvirus saimiri requires STAT5 pathways
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Article
Open AccessThe role of STAT6 in human T cell transformation by herpesvirus saimiri
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Chapter and Conference Paper
Microwave Sintering of PM Steels
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Chapter and Conference Paper
Generalized Wiener Estimation of Three-Dimensional Current Distribution from Biomagnetic Measurements
The inherent difficulty in the biomagnetic inverse problem is that a three-dimensional current distribution must be estimated from a biomagnetic field measured on a two-dimensional surface close to a human hea...
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Chapter and Conference Paper
Interprocedural Symbolic Evaluation of Ada Programs with Aliases
Symbolic Evaluation is a technique aimed at determining dynamic properties of programs. We extend our intraprocedural data-flow framework introduced in [3] to support interprocedural symbolic evaluation. Our data...
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Article
Configuration, implementation and management of heterogeneous industrial communication networks using fieldbus technology
Fieldbuses represent the lower communication layers of industrial communication systems. There are large efforts in standardisation and in the introduction of open fieldbus protocols. However, users, manufactu...
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Article
The separation of overlap** neuromagnetic sources in first and second somatosensory cortices
In response to a somatosensory stimulus, two cortical centers in each hemisphere produce neural mass activity large enough to be detected with electric (EEG) or magnetic (MEG) measurements. Both the primary so...
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Article
New high-resolution electrostatic electron spectrometer for conversion electron Mössbauer spectroscopy
The construction and performance of a new electron spectrometer using an electrostatic 90°-spherical deflection analyzer (SDA) is described. The spectrometer is suited for depth-selective conversion-electron M...
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Article
The spin texture in Fe/Tb multilayers
Fe/Tb multilayers (ML) have been prepared in UHV. The layer thickness for Fe was varied from 10 to 80 Å with Tb-layer thicknesses of 3.5, 7, 14 and 26 Å. Different substrate temperatures Ts between Ts=130 K and R...
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Chapter and Conference Paper
Bedeutung der Nucleolar Organizer Regions für die Differentialdiagnose epidermaler und melanozytärer Hauttumoren
Als Nucleolar Organizer regions (NORs) werden nukleoläre DNA-Abschnitte bezeichnet, die an histologischen Schnittpräparaten über eine Silbermarkierung dargestellt werden können. Deren Anzahl und Größe gestatte...
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Chapter and Conference Paper
Signalverarbeitung und Quellrekonstruktion beim Biomagnetismus
In letzter Zeit hat die magnetische Ortung bioelektrischer Quellen im menschlichen Körper wieder verstärkte Aufmerksamkeit gefunden. Die Methode ist schon seit 1965 bekannt [1], doch stehen erst jetzt Vielkana...
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Article
Poster contributions
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Article
Aspects of the examination and assessment of waste
The examination of wastes shows a few special problems in contrast to that of more or less homogeneous materials like raw and finished products. Thus, high requirements have to be met for conception and techni...
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Article
The determination of substituted aromatic amines in water and sediment samples
Certain substituted aromatic amines (anilines and benzidines) are known to possess high toxicological potential. They are classical environmental pollutants by virtue of their high degree of water solubility a...
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Article
Zum Verhalten von Umweltchemikalien in künstlichen Grundwassergerinnen
Selected chemical substances (simazine, lindane, tri-, tetrachloroethene) were fed into an artificial aquifer (100 m) operated with diluted seepage water from an aerobic landfill. Numerous sampling points made...
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Article
First results of a calculation of the long range quark-antiquark potential from asymptotic QCD dynamics
Starting from the asymptotic dynamics of the quark-gluon interaction for large distances we calculate the first two terms of the divergent phase of elastic quark-antiquark scattering. This phase in turn allows...
