14 Result(s)
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Article
Multiple-slice magnetic resonance imaging can detect visceral adipose tissue reduction more accurately than single-slice imaging
Imaging methods by magnetic resonance imaging are being increasingly used to quantify visceral adipose tissue (VAT), but there is no clear consensus as to a standardized protocol. We compared the ability of tw...
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Article
Long-term stable obesity increases risk of hypertension
Although some prospective cohort studies have shown that baseline BMI is positively associated with a future incident risk for hypertension, these studies do not account for weight changes during the observati...
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An increase in high-density lipoprotein cholesterol after weight loss intervention is associated with long-term maintenance of reduced visceral abdominal fat
It is generally agreed that excess abdominal fat, in particular visceral abdominal fat (VAF), is related to an increased risk for obesity-related complications. We examined the association between metabolic ri...
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Indirect lifestyle intervention through wives improves metabolic syndrome components in men
It is well known that body weight loss through a direct (supervised) lifestyle intervention (LSI) improves obesity-related metabolic disorders. The purpose of this study was to investigate the effects of an in...
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Effects of obesity phenotype on fat metabolism in obese men during endurance exercise
The effects of obesity phenotype on fat metabolism during endurance exercise are unclear. This study aimed to investigate in obese men whether body fat distribution would influence plasma fat availability and ...
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Article
The percentage of myeloperoxidase-positive blast cells is a strong independent prognostic factor in acute myeloid leukemia, even in the patients with normal karyotype
To examine whether the percentage of myeloperoxidase (MPO)-positive blast cells is useful as a prognostic factor for acute myeloid leukemia (AML), cytochemical analysis of MPO was performed in 491 patients who...
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Article
Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL)
Methylthioadenosine phosphorylase (MTAP) is an important enzyme used for the salvage of adenine and methionine. Cells lacking this enzyme are expected to be sensitive to purine synthesis inhibitors and/or meth...
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Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans
Objective: To address the clinical implications of leptin and to re-examine the relationship between leptin and its potential humoral regulators such as insulin, nonesterified fatty acids (NEFA) and triiodothyron...
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Effect of a selective Abl tyrosine kinase inhibitor, STI571, on in vitro growth of BCR-ABL-positive acute lymphoblastic leukemia cells
By employing a new semi-quantitative assay system that includes co-culturing leukemia cells with the mouse bone marrow-derived stromal cell line MS-5, we examined the suppressive effect of a selective inhibito...
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Article
Allogeneic bone marrow transplantation improves the outcome of de novo AML with trilineage dysplasia (AML-TLD)
De novo acute myeloid leukemia (AML) with dysplastic features in erythroblasts, granulocytes and megakaryocytes, similar to those in myelodysplastic syndrome (MDS) has been described as AML with trilineage dyspla...
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Article
Colony-forming unit-megakaryocyte (CFU-meg) numbers and serum thrombopoietin concentrations in thrombocytopenic disorders: an inverse correlation in myelodysplastic syndromes
We studied both serum-free colony-forming unit-megakaryocyte (CFU-meg) numbers and serum thrombopoietin (TPO) levels in 14 patients with aplastic anemia (AA), 37 patients with myelodysplastic syndromes (MDS) a...
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New system for assessing the prognosis of refractory anemia patients
Refractory anemia (RA) is a very heterogeneous disease regarding biological and clinical features. The International Prognostic Scoring System (IPSS) was useful for assessing the prognosis in the whole group o...
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Article
107: DETERMINATION OF SURFACTANT APOPROTEIN AND PHOSPHOLIPIDS IN AMNIOTIC FLUID FOR ESTIMATING FETAL LUNG MATURITY
Measurement of disaturated phosphatidylcholine(DSPC) or phosphatidylglycerol(PG) have been proved to be useful in complicated mothers for evaluating the fetal lung maturity. But the procedure is complicated an...
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Article
DETECTION OF CIRCULATING IMMUNE COMPLEXES IN PATIENTS WITH GLOMERULONEPHRITIS
Circulating immune complexes(CIC) are involved in the pathogenesis of various renal diseases. In eighty children with renal disease, CIC were measured using the Raji cell immunofluorecent method(Theofilopoulos...
