30 Result(s)

Article

Clinical characteristics and outcome of human herpesvirus-6 encephalitis after allogeneic hematopoietic stem cell transplantation

In this retrospective analysis using the Transplant Registry Unified Management Program, we identified 145 patients with human herpesvirus (HHV)-6 encephalitis among 6593 recipients. The cumulative incidences ...

M Ogata, K Oshima, T Ikebe, K Takano, H Kanamori, T Kondo… in Bone Marrow Transplantation (2017)

Article

Impact of the presence of HLA 1-locus mismatch and the use of low-dose antithymocyte globulin in unrelated bone marrow transplantation

HLA 1-locus-mismatched unrelated donors (1MMUD) have been used in allogeneic hematopoietic stem cell transplantation (allo-HCT) for patients who lack an HLA-matched donor. We retrospectively analyzed 3313 pati...

K Kawamura, J Kanda, S Fuji, M Murata, K Ikegame, K Yoshioka… in Bone Marrow Transplantation (2017)

Article

GvHD prophylaxis after single-unit reduced intensity conditioning cord blood transplantation in adults with acute leukemia

To investigate better GVHD prophylaxis in reduced intensity conditioning umbilical cord blood transplantation (RIC-UCBT), we compared transplant outcomes after UCBT among GvHD prophylaxes using the registry da...

S Terakura, Y Kuwatsuka, S Yamasaki, A Wake, J Kanda… in Bone Marrow Transplantation (2017)

Article

A phase I/II trial of intrabone marrow cord blood transplantation and comparison of the hematological recovery with the Japanese nationwide database

Intrabone marrow cord blood transplantation (IB-CBT) was proposed as a promising treatment modality to improve hematological recovery. However, clinical advantages of IB-CBT over conventional IV CBT have been ...

N Kurita, M Gosho, Y Yokoyama, T Kato, N Obara… in Bone Marrow Transplantation (2017)

Article

Impact of graft-versus-host disease on outcomes after unrelated cord blood transplantation

The effect of graft-versus-host disease (GVHD) on transplant outcomes after unrelated cord blood transplantation (UCBT) has not been fully elucidated. We analyzed the impact of acute and chronic GVHD on outcom...

J Kanda, Y Morishima, S Terakura, A Wake, N Uchida, S Takahashi, Y Ono… in Leukemia (2017)

Article

Dismal outcome of allogeneic hematopoietic stem cell transplantation for relapsed adult T-cell leukemia/lymphoma, a Japanese nation-wide study

H Fujiwara, S Fuji, A Wake, K Kato, Y Takatsuka, T Fukuda… in Bone Marrow Transplantation (2017)

Article

Exploratory research for optimal GvHD prophylaxis after single unit CBT in adults: short-term methotrexate reduced the incidence of severe GvHD more than mycophenolate mofetil

In order to examine GvHD prophylaxis in umbilical cord blood transplantation (UCBT) in more detail, we compared transplant outcomes after UCBT for acute leukemia among GvHD prophylaxes using registry data. We ...

S Terakura, A Wake, Y Inamoto, M Murata, R Sakai… in Bone Marrow Transplantation (2017)

Article

Low-dose thymoglobulin as second-line treatment for steroid-resistant acute GvHD: an analysis of the JSHCT

A nationwide retrospective study for the clinical outcomes of 99 patients who had received thymoglobulin at a median total dose of 2.5 mg/kg (range, 0.5–18.5 mg/kg) as a second-line treatment for steroid-resis...

M Murata, K Ikegame, Y Morishita, H Ogawa, K Kaida… in Bone Marrow Transplantation (2017)

Article

High-dose cytarabine added to CY/TBI improves the prognosis of cord blood transplantation for acute lymphoblastic leukemia in adults: a retrospective cohort study

Y Arai, T Kondo, A Shigematsu, J Tanaka, S Takahashi… in Bone Marrow Transplantation (2016)

Article

Donor cell-derived hematological malignancy: a survey by the Japan Society for Hematopoietic Cell Transplantation

M Kato, T Yamashita, R Suzuki, K Matsumoto, H Nishimori, S Takahashi, K Iwato… in Leukemia (2016)

Article

Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: Incidence, risk factors and outcomes

This retrospective study was conducted in Japan to determine the incidence, risk factors and outcomes of sinusoidal obstruction syndrome (SOS) after allogeneic hematopoietic stem cell transplantation (HSCT). A...

K Yakushi**, Y Atsuta, N Doki, A Yokota, H Kanamori… in Bone Marrow Transplantation (2016)

Article

Early application of related SCT might improve clinical outcome in adult T-cell leukemia/lymphoma

Allogeneic hematopoietic SCT (allo-HSCT) is a curative treatment for aggressive adult T-cell leukemia/lymphoma (ATLL). Considering the dismal prognosis associated with conventional chemotherapies, early applic...

S Fuji, H Fujiwara, N Nakano, A Wake, Y Inoue, T Fukuda… in Bone Marrow Transplantation (2016)

Article

Impact of conditioning intensity and TBI on acute GVHD after hematopoietic cell transplantation

The impact of the conditioning intensity and TBI on acute GVHD (aGVHD) is still a matter of debate. We analyzed 6848 adult recipients who received allogeneic hematopoietic cell transplants (HCT) between 2006 a...

H Nakasone, T Fukuda, J Kanda, T Mori, S Yano, T Kobayashi… in Bone Marrow Transplantation (2015)

Article

Impact of HLA allele mismatch on the clinical outcome in serologically matched related hematopoietic SCT

In unrelated hematopoietic SCT (HSCT), HLA allele mismatch has been shown to have a significant role. To clarify the importance of HLA allele mismatch in the GVH direction in related HSCT, we retrospectively e...

S Fuji, J Kanda, S Kato, K Ikegame, S Morishima, T Miyamoto… in Bone Marrow Transplantation (2014)

Article

Unrelated cord blood transplantation vs related transplantation with HLA 1-antigen mismatch in the graft-versus-host direction

Little information is available regarding whether an unrelated cord blood (UCB) unit or a related donor with a 1-antigen mismatch at the HLA-A, HLA-B or HLA-DR locus in the graft-versus-host direction (RD/1AG-...

J Kanda, T Ichinohe, S Kato, N Uchida, S Terakura, T Fukuda, M Hidaka, Y Ueda… in Leukemia (2013)

Article

Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation

Although fluoroquinolones or other antibiotics are commonly used to prevent bacterial infections after hematopoietic cell transplantation (HCT), because of the growing presence of multidrug-resistant microorga...

J Kanda, C Mizumoto, T Ichinohe, H Kawabata, T Saito… in Bone Marrow Transplantation (2011)

Article

Impact of discontinuing fluoroquinolone prophylaxis on early mortality after allogeneic marrow or peripheral blood SCT with myeloablative conditioning

J Kanda, T Ichinohe, T Saito, K Yamashita, T Kondo… in Bone Marrow Transplantation (2010)

Article

Long-term survival after HLA-haploidentical SCT from noninherited maternal antigen-mismatched family donors: impact of chronic GVHD

J Kanda, T Ichinohe, C Shimazaki, M Hamaguchi, A Watanabe… in Bone Marrow Transplantation (2009)